Diamondbacks vs Orioles Prediction 4/7/25 MLB Picks Today

The Baltimore Orioles and Arizona Diamondbacks meet Monday in MLB action at Chase Field. Here’s a Diamondbacks vs Orioles Prediction. This article will include a Diamondbacks vs Orioles Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 4-6 on the year and play the Blue Jays, Guardians, and Reds next. The Baltimore Orioles are batting .263 on the season, have a .324 OBP, and a .419 slugging percentage. The Baltimore Orioles pitching staff has a 4.71 ERA and a 1.41 WHIP. Jordan Westburg leads the Baltimore Orioles with 11 hits and 4 RBI, while Tyler O’Neil and Ryan Mountcastle have combined for 22 hits and 8 RBI.

Zach Eflin gets the ball for the Baltimore Orioles, and he is 1-1 with a 3.75 ERA and 7 strikeouts this season. Eflin is 0-2 with a 3.18 ERA and 24 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 5-5 on the year and play the Brewers, Marlins, and Cubs next. The Arizona Diamondbacks are batting .261 on the season, have a .350 OBP, and a .450 slugging percentage. The Arizona Diamondbacks pitching staff has a 5.07 ERA and a 1.24 WHIP. Geraldo Perdomo leads the Arizona Diamondbacks with 11 hits and 12 RBI while Corbin Carroll and Josh Naylor have combined for 21 hits and 10 RBI.

Zac Gallen gets the ball for the Arizona Diamondbacks, and he is 1-1 with a 3.38 ERA and 17 strikeouts this season. Gallen is 1-1 with a 5.56 ERA and 8 strikeouts in his career against the Baltimore Orioles.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won six of their last seven home games against American League opponents.
• The Orioles have lost five of their last six night games against National League opponents.
• The Diamondbacks have covered the run line in each of their last four games against the Orioles following a road loss.
• The Orioles have failed to cover the run line in five of their last six night games against NL West opponents.
• The Diamondbacks have won the first inning in five of their last six night games against American League opponents that held a losing record.
• The Diamondbacks have led after 5 innings in seven of their last eight night games against AL East opponents that held a losing record.
• The Orioles have trailed after 3 innings in seven of their last eight games as underdogs against National League opponents.

Why the Baltimore Orioles will win

• The Orioles have won each of their last six games as road underdogs following a loss.
• The Diamondbacks have lost four of their last five games as favorites against AL East opponents.
• The Orioles have covered the run line in each of their last six games as road underdogs following a loss.
• The Diamondbacks have failed to cover the run line in each of their last five games as home favorites following a road loss.
• The Orioles have led after 3 innings in seven of their last eight road night games.
• The Diamondbacks have lost the first inning in each of their last four games.
• The Diamondbacks have trailed after 5 innings in five of their last six home games against opponents that held a losing record.

Diamondbacks vs Orioles Prediction

Eflin in the underdog role is attractive, but the Orioles aren’t stringing together much offense at the moment, and it makes them a tough sell, especially on the road. The Diamondbacks are coming off a tough series against the Nationals, but the offense has been consistent and that’s encouraging coming back home. Also, Gallen has been a strikeout machine through two games, and he just mowed down the Yankees lineup a few days ago. Gallen is one of the better pitchers in baseball when he’s right, and you don’t often get him with prices this soft. I’ll gladly take the Diamondbacks at home with their ace on the bump.