Diamondbacks vs Phillies Prediction 9/19/25 MLB Picks Today

The Philadelphia Phillies and Arizona Diamondbacks meet Friday in MLB action at Chase Field. Here’s a Diamondbacks vs Phillies Prediction. This article will include a Diamondbacks vs Phillies Pick.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 91-62 on the year and play the Marlins and Twins next. The Philadelphia Phillies are batting .259 on the season, have a .330 OBP, and a .431 slugging percentage. The Philadelphia Phillies pitching staff has a 3.86 ERA and a 1.24 WHIP. Trea Turner leads the Philadelphia Phillies with 179 hits and 69 RBI, while Kyle Schwarber and Nick Castellanos have combined for 270 hits and 194 RBI.

Taijuan Walker gets the ball for the Philadelphia Phillies, and he is 5-8 with a 4.17 ERA and 79 strikeouts this season. This will be Walker’s second career game against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 77-76 on the year and play the Dodgers and Padres next. The Arizona Diamondbacks are batting .251 on the season, have a .324 OBP, and a .434 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.44 ERA and a 1.31 WHIP. Geraldo Perdomo leads the Arizona Diamondbacks with 162 hits and 97 RBI while Corbin Carroll and Lourdes Gurriel Jr. have combined for 263 hits and 158 RBI.

Ryne Nelson gets the ball for the Arizona Diamondbacks, and he is 7-3 with a 3.34 ERA and 122 strikeouts this season. Nelson is 0-1 with a 4.15 ERA and 18 strikeouts in his career against the Philadelphia Phillies.

Philadelphia Phillies @ Arizona Diamondbacks Betting Trends: September 19, 2025

 

Why the Arizona Diamondbacks will win

 

Why the Philadelphia Phillies will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Philadelphia Phillies Player Prop Facts

Matchup/League Facts

Diamondbacks vs Phillies Prediction

The Phillies are the better team, but Walker has been hittable all season, and he’s allowed 22 hits and 13 runs in his last 15 innings. Walker has allowed 17 runs in his last 20 innings. Nelson has allowed 17 hits and 5 runs in his last 24 innings. In 75.1 home innings, Nelson has a 2.51 ERA and .200 allowed batting average. The Diamondbacks are also fighting for their wild card lives, while the Phillies are in a comfortable spot in the NL. Pretty close to a must win game for the Diamondbacks. I’ll lay the reasonable price.

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