Diamondbacks vs Rays Prediction 4/22/25 MLB Picks Today

In this article, we will formulate a Diamondbacks vs Rays prediction for this MLB game on Tuesday, April 22nd at Chase Field in Phoenix, Arizona. Let’s take a look at the prediction for this MLB matchup. 

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 13-9 this year after they lost two out of three against the Cubs by scores of 11-13, 2-6, and 3-2. In their game three win, the Diamondbacks tied the game at one in the fourth inning, but didn’t score again until the 10th, and ended up winning in the 11th. The Diamondbacks recorded eight hits and they recorded two errors in the game, while they were led by Naylor, who went 3-5 with two RBIs in the win. Arizona started Kelly, who allowed two hits and one earned run over 5.2 innings, while Miller got the win and Jameson got the save. 

Prior to that series, the Diamondbacks swept the Marlins in three games and won two out of three against the Brewers. Arizona has won six of its last eight games, and they are currently fourth in the NL West standings. The Arizona pitching staff has a 4.43 ERA with a 1.22 WHIP and a .234 opponent batting average, while their offense has scored 120 runs with a .251 batting average and a .340 on-base percentage this year. Corbin Carroll has led Arizona with seven home runs and 19 RBIs, while Geraldo Perdomo has added three home runs and 19 RBIs this season. The projected starting pitcher for Arizona is Brandon Pfaadt, who is 3-1 with a 3.04 ERA and a 1.10 WHIP over 23.2 innings pitched this year. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 9-13 this season after they lost three out of four against the Yankees by scores of 3-6, 0-1, 10-8, and 0-4. In their game four loss, Tampa Bay fell behind in the first inning and couldn’t find any offense in the game to get back into it. The Rays recorded just two hits in the game, and they were led by Mangum and Simpson, who both had one hit in the loss. TB started Pepiot, who allowed six hits and three earned runs over 6.0 innings in the loss, while Cleavinger allowed one hit and one earned run in one inning of relief work. 

Prior to that series, the Rays lost two out of three against the Red Sox, but did win two out of three against the Braves before that. Tampa Bay has lost five of its last six games, and they are last in the AL East standings. The Tampa Bay pitching staff has a 3.66 ERA with a 1.17 WHIP and a .234 opponent batting average, while the offense has scored 94 runs with a .258 batting average and a .326 on-base percentage this season. Junior Caminero has led Tampa Bay with five home runs and 11 RBIs, while Jonathan Aranda has added four home runs and 13 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Zack Littell, who is 0-4 with a 5.48 ERA and a 1.26 WHIP over 23.0 innings pitched this year. 

Why the Diamondbacks will beat the Rays

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Tampa Bay Rays Player Prop Facts

Matchup/League Facts

Diamondbacks vs Rays Prediction 

Arizona comes into this series with a 13-9 record on the season, but they are just fourth in the highly competitive NL West. The Diamondbacks are 6-4 at home this year, while the Rays are 0-3 on the road. Tampa Bay has really struggled over the last week, and they have been shut out in three of their last five games. Arizona’s pitching staff has been below average to start the season, but Pfaadt has had two very good starts in a row. Tampa Bay is going with Littell, who has allowed at least five runs in two of his last three starts. Take Arizona -1.5 here. 

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