Giants vs Brewers Prediction 4/22/25 MLB Picks Today

The Milwaukee Brewers and the San Francisco Giants meet Tuesday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Giants vs Brewers Prediction.

Starting Pitching Matchup

The Milwaukee Brewers will send Jose Quintana for the start here, and Quintana is 2-0 with a 0.71 ERA and 6 strikeouts this season. In his last five starts against the Giants, Quintana is 1-3 with a 5.06 ERA and 21 strikeouts. Jordan Hicks will get the start for the Giants and is 1-2 with a 6.04 ERA and 19 strikeouts this season. This will be Hicks’ first career start against the Brewers.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to bounce back from a 5-2 loss to start the series in Monday’s matchup. After this series, the Brewers will head on the road for a series against the Cardinals.

Brewers Looking To Even Up Series

Brice Turang has a team-high 28 hits with 3 home runs, 11 RBIs, and 8 stolen bases, while Jackson Chourio has 26 hits with a team-high 8 doubles, 5 home runs, and 19 RBIs, and Sal Frelick has 27 hits as well as 7 stolen bases so far this season. Christian Yelich also has 5 stolen bases with 4 homers and 15 RBIs, while Isaac Collins has added 3 doubles. Chourio also has a team-high 25 strikeouts up to this point in the year. William Contreras has 3 homers and 13 RBIs as well this season.

Why the Milwaukee Brewers will win

Milwaukee Brewers Player Prop Facts

San Francisco Giants Recap

The San Francisco Giants come into this game looking to build on Monday’s series-opening win to improve to 15-8 on the year. After this series, the Giants will welcome the Texas Rangers to town.

Giants Looking For Consistency

Jung Hoo Lee leads the Giants with 28 hits, including a team-high 10 doubles along with a pair of triples, 3 home runs, and 15 RBIs with 3 stolen bases, while Heliot Ramos has 21 hits with 7 doubles, 3 home runs, and 9 RBIs. Wilmer Flores also has a team-high 7 home runs and 24 RBIs, while Mike Yastrzemski has 3 home runs with 11 RBIs and 6 doubles, and Tyler Fitzgerald has a team-high 5 stolen bases as well on the year.

Why the San Francisco Giants will win

San Francisco Giants Player Prop Facts

Total Runs Facts

Giants vs Brewers Prediction

I’m on the Brewers here. I get why the Giants would be worth the look at home, but the thing about Jordan Hicks is he’s a flamethrower, but he puts so much behind those pitches. He gases himself far too early in his starts and either gets hit hard or puts a lot of strain on the Giants’ bullpen. Milwaukee has a solid bullpen, and Quintana’s been fantastic out of the gate, and I think the Brewers even up the series here. Give me the Brew Crew on the road.

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