Giants vs Mariners Prediction 4/5/25 MLB Picks Today

The Seattle Mariners and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. San Francisco Giants prediction.

Starting Pitching Matchup

The Seattle Mariners will start Bryce Miller here and Miller is 0-1 with a 4.76 ERA and 4 strikeouts this season. This will be Miller’s first career start against the Giants. The San Francisco Giants will give the nod to Robbie Ray here and Ray is 1-0 with a 5.06 ERA and 4 strikeouts this season. In his last five starts against the Mariners, Ray is 1-0 with a 2.89 ERA and 37 strikeouts.


Seattle Mariners Recap

The Seattle Mariners come into this game looking to bounce back from a 10-9 loss at the hands of the Giants in Friday’s series opener to fall to 3-5 on the year. After this series, the Mariners will return home for a series with the Houston Astros.

Mariners Looking To Get Back On Track

Jorge Polanco leads the Mariners with 9 hits including a pair of home runs and 8 RBIs while Victor Robles has 8 hits with a team-high 3 doubles. Randy Arozarena has 4 hits with a pair of doubles and a pair of home runs but also leads Seattle with 11 strikeouts as well on the year. Julio Rodriguez has chipped in 7 hits with 2 home runs and a triple and a team-high 3 stolen bases while Cal Raleigh and Ryan Bliss have each added a pair of stolen bags as well on the year.

Why the Seattle Mariners will win

Seattle Mariners Player Prop Facts

San Francisco Giants Recap

The San Francisco Giants will try to keep the momentum going after a thrilling win over the Mariners in Friday’s opener to improve to 6-1 on the year. After this game, the Giants will welcome the Cincinnati Reds to town for an interleague series.

Giants Win 5th Straight

Heliot Ramos leads the Giants with 10 hits including a team-high 3 doubles along with 3 home runs and 8 RBIs but also leads the Giants with 12 strikeouts so far this season while Wilmer Flores has a team-high 4 home runs and 10 RBIs as well this season. Jung Hoo Lee also has a team-high 3 doubles while Lamonte Wade Jr. has 4 hits with 2 doubles, a triple and a home run. Willy Adames has also contributed 6 hits with a pair of doubles and 6 RBIs and Matt Chapman’s added a pair of homers and 6 RBIs as well this season.

Why the San Francisco Giants will win

San Francisco Giants Player Prop Facts

Total Runs Facts

Seattle Mariners vs. San Francisco Giants Prediction

I’m on the Giants in this game. The Mariners had an odd offensive explosion in Friday’s opener but I’m not trusting that to be sustainable against the Giants two days in a row. The Mariners weren’t great offensively last year, and haven’t been great this year either, but last year, the Mariners also stunk against left-handed pitching. This year, the Mariners have struck out early and often against southpaws, which should bode well against a strikeout artist like Robbie Ray. I think the Giants go for the sweep on Sunday, so give me San Francisco to get the win on Saturday.

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