Guardians vs Astros Prediction 6/7/25 MLB Picks Today

The Houston Astros and Cleveland Guardians meet Saturday in MLB action at Progressive Field. Here’s a Guardians vs Astros Prediction. This article will include a Guardians vs Astros Pick.

Houston Astros Betting Preview

The Houston Astros are 35-28 on the year and play the White Sox, Twins, and Athletics next. The Houston Astros are batting .253 on the season, have a .319 OBP, and a .391 slugging percentage. The Houston Astros’ pitching staff has a 3.54 ERA and a 1.16 WHIP. Jeremy Pena leads the Houston Astros with 78 hits and 31 RBI, while Jose Altuve and Isaac Paredes have combined for 123 hits and 61 RBI.

Hunter Brown gets the ball for the Houston Astros, and he is 8-3 with a 1.83 ERA and 84 strikeouts this season. This will be Brown’s second career game against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 33-29 on the year and play the Reds, Mariners, and Giants next. The Cleveland Guardians are batting .234 on the season, have a .305 OBP, and a .378 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.99 ERA and a 1.38 WHIP. Jose Ramirez leads the Cleveland Guardians with 75 hits and 29 RBI, while Steven Kwan and Carlos Santana have combined for 124 hits and 50 RBI.

Gavin Williams gets the ball for the Cleveland Guardians, and he is 5-3 with a 3.79 ERA and 66 strikeouts this season. This will be Williams’ second career game against the Houston Astros.

Why the Cleveland Guardians will win

• The Astros have lost each of their last six day games following a road win.
• The Guardians have won four of their last five games as home underdogs against AL West opponents.
• The Guardians have covered the run line in each of their last nine Saturday day games against American League opponents.
• The Astros have failed to cover the run line in each of their last six day games following a road win.
• The Astros have trailed after 5 innings in six of their last seven games against AL Central opponents that held a winning record.

Why the Houston Astros will win

• The Astros have won eight of their last nine games against the Guardians.
• The Guardians have lost five of their last six games against AL West opponents that held a winning record.
• The road team has covered the run line in seven of the Astros’ last eight games.
• The Guardians have failed to cover the run line in five of their last six home games against teams that held a winning record.
• The Astros have won the first inning in three of their last four day games against opponents that held a winning record.
• The Guardians have trailed after 3 innings in six of their last eight games as home underdogs against AL West opponents.
• The Guardians have trailed after 5 innings in each of their last six home games against opponents that held a winning record.

Cleveland Guardians Player Prop Facts

• Carlos Santana has hit a home run in each of his last two appearances in day games against AL teams that held a winning record.
• Nolan Jones has recorded at least one RBI in five of the Guardians’ last six day games.
• Steven Kwan has scored at least one run in each of his last eight Saturday day appearances at Progressive Field.
• Jose Ramirez has recorded at least one hit in each of his last 23 appearances after playing the previous day.
• Steven Kwan has recorded at least one Single in each of his last eight appearances with the Guardians as home underdogs against AL West opponents.
• Steven Kwan has recorded at least one Double in three of his last four appearances in day games against AL teams that held a winning record.
• Jose Ramirez ranks 4th amongst qualified players for Batting Average (.329) this season.

Houston Astros Player Prop Facts

• Jose Altuve has recorded at least one hit in each of his last nine appearances against the Guardians.
• Yordan Alvarez has recorded at least one RBI in each of his last six road appearances against AL opponents that held a winning record.
• Yordan Alvarez has scored at least one run in each of his last six road appearances against AL opponents that held a winning record.
• Brendan Rodgers has hit a home run in each of his last two appearances against the Guardians.
• Jeremy Pena has recorded at least one Single in each of the Astros’ last 12 games against AL Central opponents.
• Jose Altuve has recorded at least one Double in three of his last four appearances at Progressive Field.
• Hunter Brown ranks T1st in the league for Wins (8) this season.

Guardians vs Astros Prediction

The Guardians have been hit or miss these last couple of weeks, mainly because the offense just isn’t producing consistently. So, while Williams has been solid this season with his 3.79 ERA on the season and a 3.38 ERA in 34.2 home innings, it doesn’t mean much if the Guardians keep showing up with cold bats. Brown is an all-star pitcher this season, which includes allowing 23 hits and 10 runs in his last 36.2 innings. Brown has a top-five ERA and a top-10 WHIP this season, and he has a 2.51 ERA and .206 allowed batting average in 43 road innings. I’m not stepping in front of that. Give me the Astros and the cheap price.