Guardians vs Dodgers Prediction 5/28/25 MLB Picks Today

The Los Angeles Dodgers and the Cleveland Guardians meet Wednesday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Guardians vs Dodgers Prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Clayton Kershaw for the start here, and Kershaw is 0-0 with a 7.50 ERA and 3 strikeouts this season. In his career, Kershaw is 1-0 with a 3.79 ERA and 17 strikeouts against the Guardians. Cleveland will send Slade Cecconi for the start here, and Cecconi is 1-1 with a 3.27 ERA and 14 strikeouts this season. This will be Cecconi’s first career start against the Dodgers.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to build on their 9-5 win over the Guardians from Tuesday’s matchup to improve to 34-21 on the year. After this series, the Dodgers will head home for a headliner series against the New York Yankees.

Dodgers Pick Up 5th Win In Last 7

Shohei Ohtani has 62 hits, including 9 doubles, 19 home runs, 33 RBIs, and 4 triples, while Tommy Edman has 31 hits with 8 home runs and 26 RBIs. Michael Conforto has 25 hits with 9 doubles, while Teoscar Hernandez has 47 hits with 10 home runs, 13 doubles, and 42 RBIs as well this season. Ohtani has a team-high 11 stolen bases, while Max Muncy has 8 doubles but also has 50 strikeouts so far this season. Mookie Betts has also chipped in 8 home runs and 31 RBIs on the year. Freddie Freeman has also logged 57 hits with a team-high 14 doubles, 9 home runs, and 35 RBIs.

Why the Los Angeles Dodgers will win

Los Angeles Dodgers Player Prop Facts

Cleveland Guardians Recap

The Cleveland Guardians will be out to bounce back from their loss at the hands of the Dodgers on Tuesday to drop to 29-25 on the year. After this series, the Guardians will take on the Los Angeles Angels at home.

Guardians Lose Third Straight

Steven Kwan leads the Guardians with 65 hits as part of a .314 batting average and 4 home runs, 12 doubles, and 19 RBIs. Kyle Manzardo has 36 hits with 6 doubles, 2 triples, 10 home runs, and a team-high 28 RBIs this year. Gabriel Arias has 9 doubles but also 52 strikeouts, and Manzardo has 52 strikeouts so far this season. Arias has also added 4 home runs and 20 RBIs, and Jose Ramirez has chipped in 9 home runs and 26 RBIs. Carlos Santana has also added 40 hits with 6 home runs and 27 RBIs this season.

Why the Cleveland Guardians will win

Cleveland Guardians Player Prop Facts

Total Runs Facts

Guardians vs Dodgers Prediction

I’m on the Dodgers here. I just think that the Dodgers have Cleveland’s number in this series, and Slade Cecconi isn’t going to convince me otherwise. Cecconi may have had a decent start to this season, but in two career relief appearances, he’s been shelled against the Dodgers, and I think the Dodgers get to him here. Cleveland hasn’t been as sharp against lefties, and I think this could be a good spot for Clayton Kershaw. Give me the Dodgers here.

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