Guardians vs Orioles Prediction 7-21-25 MLB Picks

The Baltimore Orioles and Cleveland Guardians meet Monday in MLB action at Progressive Field. Here’s a Guardians vs Orioles Prediction. This article will include a Guardians vs Orioles Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 44-54 on the year and play the Rockies, Blue Jays, and Cubs next. The Baltimore Orioles are batting .239 on the season, have a .303 OBP, and a .398 slugging percentage. The Baltimore Orioles pitching staff has a 4.96 ERA and a 1.41 WHIP. Gunnar Henderson leads the Baltimore Orioles with 97 hits and 34 RBI, while Jackson Holliday and Ryan O’Hearn have combined for 173 hits and 75 RBI.

Tomoyuki Sugano gets the ball for the Baltimore Orioles, and he is 7-5 with a 4.44 ERA and 59 strikeouts this season. This will be Sugano’s second career game against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 48-50 on the year and play the Royals, Rockies, and Twins next. The Cleveland Guardians are batting .223 on the season, have a .295 OBP, and a .370 slugging percentage. The Cleveland Guardians pitching staff has a 3.96 ERA and a 1.34 WHIP. Jose Ramirez leads the Cleveland Guardians with 105 hits and 52 RBI, while Steven Kwan and Carlos Santana have combined for 176 hits and 74 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 5-9 with a 4.29 ERA and 95 strikeouts this season. Bibee is 1-1 with a 5.40 ERA and 12 strikeouts in his career against the Baltimore Orioles.

Why the Cleveland Guardians will win

Why the Baltimore Orioles will win

Cleveland Guardians Player Prop Facts

Baltimore Orioles Player Prop Facts

Guardians vs Orioles Prediction

This should be a high-scoring game, as Sugano has been hittable all year, and that includes allowing 14 hits and nine runs in his last 10.2 innings. Sugano is allowing a .272 batting average on the season. Bibee has allowed 16 hits and 11 runs in his last 14.1 innings. Both teams should have a field day offensively with these two pitchers being in rough shape. I expect some fireworks. Give me the over.

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