Guardians vs Twins Prediction 7/22/26 MLB Picks Today

In this article we will formulate a Guardians vs Twins prediction for this MLB game on Wednesday, July 22nd at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 54-48 this year after they won the first two games in this series by scores of 13-4 and 5-2. In game two, Cleveland blew a 2-1 lead in the fourth inning, but they scored the last three runs for the win. The Guardians recorded nine hits and they committed two errors in the game, while they were led by Rocchio, who went 2-4 with one RBI. Messick allowed four hits and one earned run over 5.2 innings, while Holderman got the win and Smith picked up the save. Prior to this series, Cleveland lost two out of three against the Pirates, but did sweep the Marlins in three games before that. 

This season, Cleveland has a 3.73 ERA with a 1.26 WHIP and a .238 opponent batting average, while they have scored 410 runs with a .233 batting average and a .313 on base percentage. Chase DeLauter has led the Guardians with 11 home runs and 50 RBIs, while Angel Martinez has added 11 home runs and 33 RBIs. The projected starting pitcher for Cleveland is Slade Cecconi, who is 4-6 with a 4.55 ERA and a 1.41 WHIP over 99.0 innings pitched this year. 

Minnesota Twins Betting Preview

The Minnesota Twins are 49-53 this season after they lost game two by a score of 2-5 on Tuesday. Minnesota led 1-0 in the first inning, but they scored just one run in the final eight innings for the loss. The Twins recorded six hits in the game and they were led by Jeffers, who went 1-4 with one home run and one RBI. Rojas opened the game, while Paredes allowed six hits and two earned runs over 3.0 innings for the loss. Prior to this series, Minnesota lost two out of three against the Cubs, but did win two out of three against the Angels before that. 

This season, Minnesota has a 4.75 ERA with a 1.40 WHIP and a .255 opponent batting average, while they have scored 485 runs with a .247 batting average and a .321 on base percentage. Byron Buxton has led the Twins with 25 home runs and 45 RBIs, while Josh Bell has added 13 home runs and 60 RBIs. The projected starting pitcher for Minnesota is Bailey Ober, who is 7-3 with a 4.32 ERA and a 1.19 WHIP over 77.0 innings pitched this season. 

Why the Cleveland Guardians will win

Why the Minnesota Twins will win

Total Runs Facts

Cleveland Guardians Player Prop Facts

Minnesota Twins Player Prop Facts

Guardians vs Twins Prediction 

Minnesota comes into this matchup on a four game losing streak and they have allowed 34 runs during that span. The Twins are 23-28 on the road this year, while the Guardians are 27-24 at home. Cleveland has won three of their last five games and they are tied for first in the AL Central. The Guardians are starting Cecconi, who has allowed eight earned runs in his last 8.2 innings, while Ober has allowed 2, 1, 7, 4, and 3 earned runs in his last five starts. Take the over in this matchup. 

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