LA Angels vs San Diego Padres Prediction 4/17/26 MLB Picks Today

The San Diego Padres and the Los Angeles Angels meet Friday in MLB action from Angels Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. Los Angeles Angels prediction.

Starting Pitching Matchup

The San Diego Padres will send out Matt Waldron for the start here and Waldron was 0-1 with a 7.71 ERA and 3 strikeouts last season. This will be Waldron’s second career start against the Angels. Jose Soriano will start this one for the Angels and is 4-0 with a 0.33 ERA and 31 strikeouts this season. In his career, Soriano is 1-0 with a 0.69 ERA and 6 strikeouts against the Padres.

San Diego Padres Recap

The San Diego Padres come into this game looking to build on their 5-2 win over the Seattle Mariners last time out to sit at 13-6 this season. After this series, the Padres will head on the road for a series against the Colorado Rockies.

Padres Win 8 In A Row

Jackson Merrill has 19 hits with 6 doubles, 3 home runs and 13 RBIs while Ramon Laureano has 20 hits with 4 doubles, a triple, 4 home runs and 13 RBIs as well on the year. Fernando Tatis Jr. has 17 hits with 4 doubles and 10 RBIs and Xander Bogaerts has 19 hits with 2 doubles, 3 home runs and 13 RBIs. Manny Machado also has 12 hits with 2 doubles, 2 home runs and 10 RBIs as well on the year.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to add on to their 11-4 win over the Yankees last time out to sit at 10-10 this season. After this series, the Angels will take on the Toronto Blue Jays in a series at home.

Angels Alternate Wins & Losses In 8 Straight

Nolan Schanuel has 14 hits with 2 doubles, a pair of homers and 11 RBIs while Mike Trout’s added 17 hits with 3 doubles, 7 home runs and 16 RBIs this season. Zach Neto’s also added 19 hits with 4 doubles, 5 homers and 9 RBIs and Jo Adell has 25 hits with 3 home runs and 12 RBIs as well this season. Oswald Peraza has 14 hits with 3 doubles, 4 home runs and 8 RBIs and Jorge Soler has 15 hits with 3 doubles, 5 home runs and 18 RBIs well this season.

San Diego Padres @ Los Angeles Angels Betting Trends: April 17, 2026

 

Why the Los Angeles Angels will win

 

Why the San Diego Padres will win

Total Runs Facts

Los Angeles Angels Player Prop Facts

San Diego Padres Player Prop Facts

Matchup/League Facts

San Diego Padres vs. Los Angeles Angels Prediction

I’m on the Angels in this one. I get the case to be made for the Padres here, but the thing is that the Padres have a significant deficit when it comes to the advantage that the Angels have on the mound with Soriano and I think that’s enough of an advantage that the Padres’ dominant bullpen doesn’t become a factor late. I think the Angels steal this one behind another strong showing from Soriano so give me the Angels in this one.

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