Mariners vs Giants Prediction 4/6/25 MLB Picks Today

The Seattle Mariners are visiting the San Francisco Giants on Sunday, April 6^th at the Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Mariners vs Giants Prediction. We will examine:

The San Francisco Giants recent form and player performance

The Seattle Mariners recent form and player performance

Recent betting trends and streaks involving the San Francisco Giants

Recent betting trends and streaks involving the Seattle Mariners

Recent betting trends in games played between the Seattle Mariners vs San Francisco Giants

A summary that ties it all together and produces a favorable betting outcome for Seattle Mariners vs San Francisco Giants game

San Francisco Giants Preview

The San Francisco Giants have a 7-1 record this season and are sitting on the second place of the NL West. They are coming off a 4-1 home victory over the Mariners, and now have seven consecutive wins. They are 3-1 to the over in their last 4 games, and are playing the Reds and the Yankees next. The Giants have a .241 batting average this season, .313 OBP and .432 Slugging percentage. San Francisco’s pitching staff has a 2.71 ERA and 1.21 WHIP.  Heliot Ramos leads the Giants with 11 hits, while Wilmer Flores leads the team with 11 RBI and 4 home runs.

Jordan Hicks (R) will take the mound for the Giants, and in this previous start of the season, he had zero earned runs in 6 innings of work, as the Giants won the Astros by 7-2. Last season he had a 4-7 record, 4.10 ERA and 1.45 WHIP. This will be the first ever start against the Seattle Mariners.

Seattle Mariners Preview

The Seattle Mariners have a 3-6 record this season and are sitting on the last place of the AL West. They are coming off a 1-4 road defeat against the Giants, and are 1-5 in their last 6 games. They are 6-2 to the under this season, and are playing the Astros and the Rangers next. The Rays Mariners a .202 batting average this season, .312 OBP and .333 Slugging percentage. Seattle’s pitching staff has a 4.52 ERA and 1.43 WHIP. Victor Robles leads the Mariners with 10 hits and a .256 batting average, while Jorge Polanco leads the team with 8 RBI and 2 home runs.

Bryan Woo (R) will take the mound for the Mariners, and in his previous start of the season he gave up one earned run in 6 innings of work, as the Mariners won the A’s 2-1. Last season he had a 9-3 record, 2.89 ERA and 0.90 WHIP. In his previous meeting against the Giants last season, he had one earned run in 7 innings of work, as the Mariners won 4-3.

Why the San Francisco Giants will win

• The Giants have won each of their last eight games against American League opponents.
• The Mariners have lost each of their last five road games against NL West opponents that held a winning record.
• The Giants have covered the run line in each of their last seven games against American League opponents after playing the previous day.
• The Mariners have failed to cover the run line in eight of their last nine games as road underdogs against NL West opponents following a loss.
• The Giants have won the first inning in three of their last four day games against AL West opponents.
• The Giants have led after 3 innings in six of their last eight games against American League opponents.
• The Giants have led after 5 innings in each of their last eight games against American League opponents.

Why the Seattle Mariners will win

• The Giants have lost five of their last six games as favorites against AL West opponents following a home win.
• The Mariners have won eight of their last nine day games after playing the previous day.
• The Giants have failed to cover the run line in 10 of their last 11 day games against American League opponents following a home win.
• The road team has covered the run line in 10 of the Giants’ last 11 games.
• The Mariners have led after 3 innings in each of their last five Sunday road games.

Total Runs Facts

• Six of the Giants’ last seven games as favorites against AL West opponents have gone UNDER the total runs line.
• Six of the Mariners’ last seven day games against National League opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mariners’ last six day games against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the last eight day games between the Mariners and Giants.

 Mariners vs Giants Prediction

The Giants have won both previous games of this series by 10-9 and 4-1, and are 4-1 in their last 5 meetings against the Mariners. Over is 4-1-1 in their last 6 meetings.

In this Seattle Mariners vs San Francisco Giants Prediction, San Francisco is coming as -130 home favorites. The Giants are playing much better lately, but the Mariners are putting their best pitcher on the mound, so I simply cannot fade them. Both pitchers looked excellent in their previous starts, and Woo was a monster last season. I expect runs to be at a premium, especially when those two pitchers will be on the mound, so take the under the total in the first 5 innings.