Marlins vs Astros Prediction 7/21/26 MLB Picks Today

In this article, we will formulate a Marlins vs Astros Prediction for this MLB matchup on Tuesday, July 21st in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros have a 48-54 record this season and are sitting in the 3rd place of the AL West. They have a 24-27 home record and are coming off an 8-5 home win against the Marlins. They will face the White Sox and the Angels next.

The Houston Astros have a .241 batting average this season, .315 OBP and .411 Slugging percentage. Houston’s pitching staff has a 4.75 ERA and 1.40 WHIP. Yordan Alvarez is the team’s best hitter with a .324 batting average, leads the team in RBI with 75, and adds a team-high 33 home runs.

Tatsuya Imai (R) is the projected starting pitcher for the Houston Astros, and he has a 5-4 record, 6.06 ERA and 1.50 WHIP.

Miami Marlins Preview

The Miami Marlins have a 52-49 record this season and are sitting in the 3rd place of the NL East. They have a 21-29 away record and are coming off a 5-8 road loss against the Astros. They will face the Padres and the Phillies next.

The Miami Marlins have a .252 batting average this season, .328 OBP and .408 Slugging percentage. Miami’s pitching staff has a 4.05 ERA and 1.25 WHIP. Otto Lopez is the team’s best hitter with a .335 batting average. Liam Hicks leads the team in RBI with 60, adding a team-high 14 home runs.

Tyler Phillips (R) is the projected starting pitcher for the Miami Marlins, and he has a 2-4 record, 3.48 ERA and 1.39 WHIP.

Miami Marlins @ Houston Astros Betting Trends: July 21, 2026

 

Why the Houston Astros will win

 

Why the Miami Marlins will win

Total Runs Facts

Houston Astros Player Prop Facts

Miami Marlins Player Prop Facts

Matchup/League Facts

Marlins vs Astros Prediction

The Astros are 8-1 in their last 9 meetings against the Marlins and have won their last four meetings in Houston.

In this Marlins vs Astros Prediction, the Astros are coming as -125 home favorites. Yesterday’s game had 13 total runs and I also like the over in this one with two struggling pitchers on the mound. Imai has been terrible at home with a 7.92 ERA while Phillips has been in very bad form with a 6.75 ERA across his last three starts and also has a 6.53 road ERA. The Astros are averaging 6.1 runs per game against righties in their last 10 games, so I like the over 9 runs in this one.

 

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