Marlins vs Diamondbacks Prediction 4/16/25 MLB Picks Today

The Arizona Diamondbacks and the Miami Marlins meet Wednesday in MLB action from LoanDepot Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Marlins vs Diamondbacks Prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Brandon Pfaadt for the start here, and Pfaadt is 2-1 with a 3.50 ERA and 12 strikeouts this season. In his career, Pfaadt is 1-1 with an 8.71 ERA and 7 strikeouts against the Marlins. Max Meyer will get the start for Miami here and is 1-1 with a 2.00 ERA and 19 strikeouts this season. This will be Meyer’s first career start against Arizona.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to keep the ball rolling after a 10-4 win over the Marlins in Tuesday’s series opener to improve to 10-7 on the year. After this series, the Diamondbacks will head on the road for a weekend set against the Chicago Cubs.

Diamondbacks Looking For Third Straight Series Win

Corbin Carroll has a team-high 23 hits with 6 home runs, 15 RBIs, and 7 doubles, while Josh Naylor has 21 hits with 6 doubles as well this season. Eugenio Suarez has also added 5 home runs and 11 RBIs, while Geraldo Perdomo has a team-high 16 RBIs. Naylor has also chipped in a team-high 4 stolen bases as well up to this point in the year, while Suarez has the unfortunate distinction of leading the Diamondbacks with 21 strikeouts so far this season.

Why the Arizona Diamondbacks will win

Arizona Diamondbacks Player Prop Facts

Miami Marlins Recap

The Miami Marlins come into this game looking to bounce back after starting the series on the wrong foot and ending up at 8-8 on the year as a result. After this set, the Marlins will head on the road for a division series against the Philadelphia Phillies.

Marlins Looking To Rebound

Xavier Edwards leads the Marlins with 20 hits, including 3 doubles and a team-high 6 stolen bases, while Graham Pauley has 4 doubles. Otto Lopez has 14 hits with 4 doubles and a pair of home runs with 8 RBIs, and Matt Mervis has a team-high 5 home runs and 11 RBIs so far this year. Kyle Stowers has 16 hits with 3 doubles, a triple, a home run, and 10 RBIs, but also leads the Marlins with 18 strikeouts so far this season. Griffin Conine’s also chipped in 16 hits with a team-high 5 doubles as well this season.

Why the Miami Marlins will win

Miami Marlins Player Prop Facts

Total Runs Facts

Marlins vs Diamondbacks Prediction

I’m on the over here. I just can’t get there with Arizona at this price, as I still have trust issues with Brandon Pfaadt. He’s had issues against the Marlins in limited action in his career, and you could argue this is the best the Marlins’ lineup has looked from a production standpoint in some time, early on this year. On the other side, Meyer faces a tough Arizona lineup that can produce runs as well, but the Miami bullpen has been problematic as well this season, so I think the Fish will allow a few runs here as well. Give me the over.

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