Twins vs Athletics Prediction 8/21/25 MLB Picks Today

The Athletics and the Minnesota Twins meet Thursday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Twins vs Athletics Prediction.

Starting Pitching Matchup

The Athletics will send out Jack Perkins for the start here and Perkins is 2-2 with a 4.28 ERA and 35 strikeouts this season. This will be Perkins’ first career start against the Minnesota Twins. The Minnesota Twins did not have a starting pitcher announced at the time that this article was posted.

Athletics Recap

The Athletics will be looking to add on to their 4-2 win over the Minnesota Twins from Wednesday’s matchup to sit at 58-70 this season. After this series, the Athletics will head on the road for a series against the Seattle Mariners.

Athletics Win 7 Of Last 10

Jacob Wilson has 115 hits, 17 doubles and a .312 batting average while Tyler Soderstrom has 121 hits with 24 doubles, 23 home runs and 74 RBIs this season. Brent Rooker has 135 hits with 30 doubles, 25 home runs and 72 RBIs but also has 124 strikeouts this season while Nick Kurtz has a team-high 25 home runs and 67 RBIs with 23 doubles. Shea Langeliers has 99 hits with 28 home runs and 60 RBIs while Lawrence Butler’s also chipped in 17 stolen bases and 27 doubles as part of his 106 hits as well as 17 home runs and 48 RBIs while also owning a team-high 146 strikeouts this season.

Why the Athletics will win

Athletics Player Prop Facts

Minnesota Twins Recap

The Minnesota Twins come into this game looking to bounce back from a loss at the hands of the Athletics on Wednesday to slip to 58-68 this season. After this series, the Twins will take to the road for a series against the Chicago White Sox.

Twins Lose 8 Of Their Last 11

Byron Buxton has 99 hits along with 15 doubles, a team-high 25 home runs and 61 RBIs with 18 stolen bases and 4 triples while Trevor Larnach’s chipped in 98 hits with 17 doubles, 16 home runs and 50 RBIs as well this season. Brooks Lee has contributed 93 hits with 13 doubles, 13 home runs and 53 RBIs and Matt Wallner has 16 homers and 28 RBIs as well.

Why the Minnesota Twins will win

Minnesota Twins Player Prop Facts

Total Runs Facts

Twins vs Athletics Prediction

I’m on the Athletics in this one. The Twins just can’t get themselves back on track and as the days go by, it’s evident that this is a Twins’ lineup that’s just playing out the string. The Athletics actually look like a team that wants to improve and wants to build something for the future, while the Twins unloaded the shelves at the trade deadline. They took no prisoners when it came to offloading starters to stockpile assets going forward. I just think that the Athletics are the better team right now, and I just want no part of the Twins in their current form, regardless of who is starting on the mound here. Give me the Athletics here.

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