Orioles vs Guardians Prediction 4/17/25 MLB Picks Today

The Cleveland Guardians and the Baltimore Orioles meet Thursday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Orioles vs Guardians Prediction.

Starting Pitching Matchup

The Cleveland Guardians will send out Tanner Bibee for the start here and Bibee is 1-1 with a 4.40 ERA and 10 strikeouts this season. This will be Bibee’s second career start against the Orioles. Tomoyuki Sugano will get the nod for the Orioles here and is 1-1 with a 3.86 ERA and 5 strikeouts this season. This will be Sugano’s first career start against the Guardians.

Cleveland Guardians Recap

The Cleveland Guardians will be out to rebound after taking one on the chin in a 9-1 loss in Wednesday’s matchup. After this series, the Guardians will head on the road once again for an interleague series with the Pittsburgh Pirates.

Guardians Looking To Win Rubber Match

Steven Kwan leads the Guardians with 21 hits as part of a .333 batting average and 3 home runs, a double and 11 RBIs. Kyle Manzardo has 9 hits with a double, a triple, 4 home runs and a team-high 11 RBIs as well this year. Nolan Jones has a team-high 3 doubles while Brayan Rocchio, Jose Ramirez and Carlos Santana all have a pair of doubles, while Jones, Manzardo and Gabriel Arias all share the team-high with 16 strikeouts so far this season.

Why the Cleveland Guardians will win

Cleveland Guardians Player Prop Facts

Baltimore Orioles Recap

The Baltimore Orioles will try to win the series after evening the set up at one win apiece thanks to their beatdown win over the Guardians on Wednesday. After this series, the Orioles will welcome the Cincinnati Reds to town for an interleague series.

Orioles Trying To String Wins Together

Cedric Mullins has a team-high 15 hits so far this season as well as team-highs of 4 doubles, 4 home runs and 17 RBIs with 3 stolen bases and a .300 batting average while Adley Rutschman has 14 hits with a pair of doubles, 3 homers and 6 RBIs. Ryan Mountcasle has 14 hits with 3 doubles and Tyler O’Neill has 13 hits with 3 doubles, a triple and 2 homers with 8 RBIs. Jordan Westburg’s added 3 home runs but also has a team-high 14 strikeouts as does Gunnar Henderson.

Why the Baltimore Orioles will win

Baltimore Orioles Player Prop Facts

Total Runs Facts

Orioles vs Guardians Prediction

I’m on the Guardians here. The Orioles definitely showed some signs of life offensively in Wednesday’s win, but the pitching staff was lucky to get themselves out of some serious jams at certain points of that game. It was a few timely hits that the Orioles had that won them the game. Maybe it’s a sign that Baltimore’s starting to turn things around, but I need more than one game to really buy what they’re selling. Bibee is supposed to be the Guardians’ staff ace, and Sugano has not drummed up many strikeouts this season, which is a concern against a patient and consistent Guardians’ lineup that’s been hitting righties well as of late. I’ll side with the Guardians to rebound and win the series finale on Thursday.

Exit mobile version