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Orioles vs White Sox Prediction 5/31/25 MLB Picks Today

Chicago White Sox (18-39) vs. Baltimore Orioles (20-36)
May 31, 2025 4:05 pm EDT
The Line: Baltimore Orioles -198 / Chicago White Sox 164; Over/Under: 9
(Get latest betting odds)

In this article we will formulate an Orioles vs White Sox prediction for this MLB game on Saturday, May 31st at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 20-36 this season after they won game one by a score of 2-1 on Friday. Baltimore scored two runs in the sixth inning, which was enough to get the low scoring win. The Orioles recorded seven hits in the game and they were led by Urias, who went 0-2 with one RBI in the win. Baltimore started Eflin, who allowed four hits and zero earned runs over 7.0 innings for the win, while Bautista picked up the save. 


Prior to this series, the Orioles lost two out of three against the Cardinals and split four games with the Red Sox. Baltimore has won four of their last six games and they are currently last in the AL East standings. The Baltimore pitching staff has a 5.41 ERA with a 1.47 WHIP and a .273 opponent batting average, while their offense has scored 215 runs with a .237 batting average and a .303 on base percentage this season. Ryan O’Hearn has led Baltimore with nine home runs and 21 RBIs, while Jackson Holliday has added six home runs and 24 RBIs this year. The projected starting pitcher for Baltimore is Dean Kremer, who is 4-5 with a 5.02 ERA and a 1.39 WHIP over 61.0 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 18-39 this year after they dropped game one in this series on Friday afternoon. Chicago wasn’t able to find much offense in this game, but they did score in the ninth inning to avoid the shutout. The White Sox recorded six hits in the game and they were led by Benintendi, who went 1-3 with one RBI in the loss. Chicago started Shuster, who opened the game, while Burke allowed five hits and two earned runs over 6.0 innings for the loss.

Prior to this series, the White Sox lost two out of three against the Mets, but did win two out of three against the Rangers. Chicago has lost four of their last five games and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.10 ERA with a 1.37 WHIP and a .245 opponent batting average, while the offense has scored 197 runs with a .221 batting average and a .293 on base percentage this season. Miguel Vargas has led Chicago with eight home runs and 26 RBIs, while Andrew Benintendi has added six home runs and 21 RBIs this year. The projected starting pitcher for Chicago is Davis Martin, who is 2-5 with a 3.45 ERA and a 1.26 WHIP over 62.2 innings pitched this year. 

Why the Orioles will beat the White Sox

  • The White Sox have lost each of their last six road games against American League opponents.
  • The Orioles have won seven of their last eight home games against AL Central opponents that held a losing record.
  • The White Sox have failed to cover the run line in four of their last five day games against AL East opponents that held a losing record.
  • The Orioles have covered the run line in five of their last six games against the White Sox following a win.
  • The White Sox have lost the first inning in three of their last four day games against American League opponents.
  • The White Sox have trailed after 3 innings in each of their last five day games against American League opponents.
  • The Orioles have led after 5 innings in each of their last four day games.

Why the White Sox will beat the Orioles

  • The Orioles have lost each of their last seven games as home favorites after playing the previous day.
  • The underdogs have won 10 of the Orioles’ last 12 games at Oriole Park at Camden Yards.
  • The Orioles have failed to cover the run line in each of their last 10 games as home favorites.
  • The White Sox have covered the run line each of their last seven games against American League opponents that held a losing record.
  • The Orioles have lost the first inning in three of their last four day games against American League opponents that held a losing record.
  • The Orioles have trailed after 3 innings in eight of their last nine Saturday day home games.
  • The Orioles have trailed after 5 innings in seven of their last eight Saturday day home games.

Total Runs Facts

  • Fourteen of the Orioles’ last 15 day games as favorites have gone OVER the total runs line.
  • Each of the White Sox’s last six day games against American League opponents have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Orioles’ last eight games as favorites against AL Central opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the White Sox’s last six day games at Oriole Park at Camden Yards.

Baltimore Orioles Player Prop Facts

  • Gary Sanchez has recorded at least one RBI in each of his last four appearances with his team as a favorite against AL opponents.
  • Gunnar Henderson has recorded a Double in each of the Orioles’ last three games against AL opponents that held a losing record.
  • Ryan Mountcastle has recorded at least one hit in each of his last 14 appearances in day games against teams that held a losing record.
  • Dean Kremer has recorded five or more strikeouts in seven of his last eight appearances at Oriole Park at Camden Yards against AL opponents that held a losing record.
  • Ryan O’Hearn has recorded at least one Single in each of the Orioles’ last seven games against AL opponents.
  • Gunnar Henderson has scored at least one run in each of the Orioles’ last seven home games against the White Sox.
  • Dean Kremer has recorded a win in three of his last four home appearances against AL opponents.
  • Dylan Carlson has hit a home run in each of the Orioles’ last two day games.

Chicago White Sox Player Prop Facts

  • Miguel Vargas has recorded a Double in each of the White Sox’s last four day games.
  • Luis Robert has recorded an RBI in four of the White Sox’s last five games against AL opponents that held a losing record.
  • Mike Tauchman has scored a run in four of his last five appearances against the Orioles.
  • Andrew Benintendi has recorded at least one Single in each of his last seven Saturday appearances against AL teams that held a losing record.
  • Miguel Vargas has recorded at least one hit in each of the White Sox’s last six games as underdogs.
  • Andrew Vaughn has hit a home run in two of his last three road appearances against the Orioles.

Orioles vs White Sox Prediction 

Baltimore was able to get a much needed win in this series on Friday afternoon and they need to take advantage of this series against the White Sox, as they try to find some momentum to get their season going. The Orioles are 10-17 at home this year, while the White Sox are 6-24 on the road. Chicago has played slightly better over the last two weeks, but they are still a very bad road team. The White Sox are going with Martin, who has allowed two earned runs or fewer in three straight starts. The Orioles are starting Kremer, who has allowed two earned runs or fewer in three of his last five starts. I really don’t trust either team in this matchup, especially offensively, so I like the under in this game. 

David Racey's Free Pick: Under 9

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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