Padres vs Diamondbacks Prediction 6/13/25 MLB Picks Today

The San Diego Padres are visiting the Arizona Diamondbacks on Friday, June 13^th at the Chase Field in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Padres vs Diamondbacks Prediction. We will examine:

The Arizona Diamondbacks’ recent form and player performance

The San Diego Padres’ recent form and player performance

Recent betting trends and streaks involving the Arizona Diamondbacks

Recent betting trends and streaks involving the San Diego Padres

Recent betting trends in games played between the San Diego Padres vs Arizona Diamondbacks

A summary that ties it all together and produces a favorable betting outcome for the San Diego Padres vs Arizona Diamondbacks game

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 34-34 record this season and are sitting in 4^th place in the NL West. The Diamondbacks have an 18-17 home record and are 31-32 in over/under. They are coming off a 5-2 home victory over the Mariners and have three straight wins. Over is 8-5 in their last 13 games, and they are playing the Rockies and the Blue Jays next.

The Diamondbacks have a .255 batting average this season, a .333 OBP, and a .449 slugging percentage. Arizona’s pitching staff has a 4.77 ERA and 1.35 WHIP. Josh Naylor leads the Diamondbacks with 76 hits, and he is the team’s best hitter with a .302 batting average. Eugenio Suarez leads the team in RBI, with 52, adding a team-high 19 home runs.

Ryne Nelson (R) is the projected starting pitcher for the Diamondbacks, and he has a 2-2 record, 4.60 ERA, and 1.11 WHIP. He has been better at home, with a 2.67 ERA in his 8 home games, but he was torched in his last start, having given up 7 runs in just 3 innings of work against the Reds. Ryne Nelson is 3-3 with an ERA of 5.61, 29 strikeouts, and 1 save in 9 appearances against the Padres in his career.

San Diego Padres Preview

The San Diego Padres have a 38-29 record this season and are sitting in third place in the NL West. They have a 17-17 road record, and are 27-38 in over/under. The Padres are coming off a 2-5 home defeat by the Dodgers, and have been alternating wins and losses for the past 8 days. Under is 7-3 in their last 10 games, and are playing the Dodgers and the Royals next.

The Padres have a .247 batting average this season, a .315 OBP, and a .375 Slugging percentage. San Diego’s pitching staff has a 3.44 ERA and 1.22 WHIP.  Manny Machado leads the Padres with 81 hits, adding a team-high .320 batting average and also leads the team in RBI, with 39. Fernando Tatis Jr. adds a team-high 13 home runs.

Stephen Kolek (R) will take the mound for the Padres, and he has a 3-1 record, 3.00 ERA, and 1.24 WHIP. He has been excellent on the road, with a 0.85 ERA across five road starts, and he is coming off back-to-back shutout starts in 10.4 innings pitched. This will be his first career start against the D-backs.

Why the Arizona Diamondbacks will win

• The home team has won each of the Diamondbacks’ last six games.
• The Padres have lost four of their last five games against NL West opponents.
• The home team has covered the run line in each of the Diamondbacks’ last six games.
• The Diamondbacks have led after 3 innings in each of their last four night games.
• The Diamondbacks have led after 5 innings in each of their last four night games.

Why the San Diego Padres will win

• The Diamondbacks have lost nine of their last 10 games as home favorites against National League opponents following a home win.
• The Padres have won eight of their last nine games as underdogs against National League opponents following a loss.
• The Padres have covered the run line in each of their last nine games as underdogs against National League opponents following a loss.
• The Diamondbacks have failed to cover the run line in 12 of their last 13 home games against National League opponents following a home win.
• The Padres have led after 5 innings in four of their last five night games against National League opponents.
• The Padres have led after 3 innings in four of their last five night games against National League opponents.

Total Runs Facts

• Each of the Padres’ last six games as road underdogs have gone UNDER the total runs line.
• Four of the Diamondbacks’ last five home games against NL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last six games as road underdogs.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Diamondbacks’ last six home games.

Matchup/League Facts

• The Diamondbacks rank T2nd in the league for doubles this season (126).
• The Diamondbacks rank 3rd in the league for home runs this season (98).
• The Padres rank 2nd in the league for strikeouts against this season (474).
• The Padres rank 4th in the league for hits allowed this season (500).

Padres vs Diamondbacks Prediction

Both teams are tied 5-5 in their last 10 meetings, while the Padres are 2-1 in their last 3 visits to Arizona. Over is 7-2 in their last 9 meetings.

In this Padres vs Diamondbacks Prediction, the Diamondbacks are coming as -135 home favorites. The wrong team is favored in this spot, as the Padres have a better overall record, and both teams have very similar home/away splits. The bullpen differential is also huge, as the Padres have the third-best bullpen ERA, while the D-backs are fourth-to-last.

The Padres also have the pitching advantage, as Kolek has been better overall and almost unhittable on the road, and I certainly trust him more than Nelson, who has been shaky this season, and has a terrible history against Dbacks bats. The value here lies with the road dog, so take the San Diego Padres on the moneyline.