Padres vs Mets Prediction 9/17/25 MLB Picks Today

In this article, we will formulate a Padres vs Mets Prediction for this MLB game on Wednesday, September 17th at the Citi Field in the second game of this series, with the Mets having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

New York Mets Preview

The New York Mets have a 78-73 record this season and are sitting on the second place of the NL East. The Mets have a 47-29 home record and are 71-72 in over/under. They are coming off an 8-3 home victory over the Padres, and have back-to-back wins. Over is 5-2 in their last 7 games and are playing the Cubs and the Nationals next.

The Mets have a .250 batting average this season, .327 OBP and .428 slugging percentage. New York’s pitching staff has a 4.01 ERA and 1.33 WHIP.  Francisco Lindor leads the Mets with 159 hits, while Pete Alonso leads the team in batting average with .268. He also adds a team-high 118 RBI, while Juan Soto adds team-high 40 home runs.

David Peterson (L) is the projected starting pitcher for the Mets, and he has a 9-5 record, 3.77 ERA and 1.32 WHIP.

San Diego Padres Preview

The San Diego Padres have an 82-69 record this season and are sitting on the second place of the NL West. They have a 35-41 road record, and are 64-81 in over/under. The Padres are coming off a 3-8 road defeat by the Mets, and have back-to-back losses. Under is 4-2 in their last 6 games and are playing the White Sox and the Brewers next.

The Padres have a .251 batting average this season, .321 OBP and .389 Slugging percentage. San Diego’s pitching staff has a 3.67 ERA and 1.20 WHIP. Louis Arraez leads the Padres with 166 hits, and he is the team’s best hitter with a .286 batting average. Manny Machado leads the team both in RBI, with 88, and in home runs, with 25.

Nick Pivetta (R) is the projected starting pitcher for the Padres, and he has a 13-5 record, 2.73 ERA and 0.95 WHIP.

San Diego Padres @ New York Mets Betting Trends: September 17, 2025

 

Why the New York Mets will win

 

Why the San Diego Padres will win

Total Runs Facts

New York Mets Player Prop Facts

San Diego Padres Player Prop Facts

Matchup/League Facts

Padres vs Mets Prediction

The Padres are 4-1 in their last 5 meetings against the Mets, but the Mets have won their last four meetings in New York. Over is 5-2 in their last 7 meetings.

In this Padres vs Mets Prediction, the Mets are coming as -115 home favorites. San Diego has the best bullpen in baseball and the pitching advantage in this game, with Pivetta on the mound. He has been elite this season, and coming into this matchup in excellent form, with a 2.10 ERA across his last 5 starts. On the flip side, Peterson has been struggling for the Mets lately, having given up 15 runs in his last three starts. I like the value with the road dog in this spot, so take the San Diego Padres on the moneyline in this one.

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