Padres vs Rays Prediction 4/27/25 MLB Picks Today

The Tampa Bay Rays and San Diego Padres meet Sunday in MLB action at Progressive Field. Here’s a Padres vs Rays Prediction. This article will include a Padres vs Rays Pick.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 13-14 on the year and play the Royals, Yankees, and Phillies next. The Tampa Bay Rays are batting .252 on the season, have a .318 OBP, and a .390 slugging percentage. The Tampa Bay Rays pitching staff has a 3.51 ERA and a 1.15 WHIP. Yandy Diaz leads the Tampa Bay Rays with 28 hits and 13 RBI, while Junior Caminero and Jonathan Aranda have combined for 50 hits and 25 RBI.


Zack Littell gets the ball for the Tampa Bay Rays, and he is 0-5 with a 5.28 ERA and 21 strikeouts this season. Littell is 1-0 with a 5.40 ERA and 17 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 17-10 on the year and play the Giants, Pirates, and Yankees next. The San Diego Padres are batting .257 on the season, have a .327 OBP, and a .392 slugging percentage. The San Diego Padres pitching staff has a 2.77 ERA and a 1.13 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 35 hits and 18 RBI, while Manny Machado and Luis Arraez have combined for 53 hits and 17 RBI.

Randy Vasquez gets the ball for the San Diego Padres, and he is 1-2 with a 3.97 ERA and 9 strikeouts this season. This will be Vasquez’s second career game against the Tampa Bay Rays.

Why the San Diego Padres will win

Why the Tampa Bay Rays will win

San Diego Padres Player Prop Facts

Tampa Bay Rays Player Prop Facts

Padres vs Rays Prediction

The Rays are having a week that includes four straight wins and an offense that’s picked up. The problem in this spot is that Littell is on the mound, a pitcher who has allowed 29 hits and 17 runs in 29 innings. Littell has allowed 16 runs alone in his last 23 innings. Littell has lost each of the last six games he’s pitched.

The Padres have lost three straight games and have scored a combined one run in those games, but this feels like what the doctor ordered for them to break out of this funk. Vasquez was rocked in his last outing, but he’s been solid overall, and that includes an ERA under four on the season. Vasquez has allowed one run in 11 home innings. Give me the Padres and the cheap price, given the gap between starting pitchers.

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