Phillies vs Guardians Prediction 5/22/26 MLB Picks Today

In this article we will formulate a Phillies vs Guardians prediction for this MLB game on Friday, May 22nd at Citizens Bank Park in Philadelphia, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 25-25 this year after they lost two out of three against the Reds by scores of 5-4, 1-4, and 4-9. In game three, Philadelphia led 1-0 in the first inning, but they allowed eight of the last eleven runs in the loss. The Phillies recorded six hits and they committed one error in the game, while they were led by Sosa, who went 1-3 with one home run and two RBIs. Nola allowed eight hits and four earned runs over 5.0 innings for the loss, while Alvarado allowed two earned runs in relief. Prior to that series, Philadelphia swept the Pirates in three games and won two out of three against the Red Sox. 

This season, Philadelphia has a 4.31 ERA with a 1.35 WHIP and a .265 opponent batting average, while they have scored 209 runs with a .231 batting average and a .300 on base percentage. Kyle Schwarber has led the Phillies with 20 home runs and 36 RBIs, while Bryce Harper has added 12 home runs and 31 RBIs. The projected starting pitcher for Philadelphia is Cristopher Sanchez, who is 5-2 with a 1.82 ERA and a 1.20 WHIP over 64.1 innings pitched this year. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 30-22 this season after they won all four games against the Tigers by scores of 8-2, 4-3, 3-2, and 3-1. In game four, Cleveland took a 2-0 lead in the third inning and never looked back in the win. The Guardians recorded six hits in the game and they were led by Bailey, who went 1-3 with one home run and one RBI. Cantillo allowed three hits and zero earned runs over 5.2 innings for the win, while Gaddis picked up the save. Prior to that series, Cleveland won two out of three against the Reds and all three against the Angels. 

This season, Cleveland has a 3.67 ERA with a 1.26 WHIP and a .234 opponent batting average, while they have scored 228 runs with a .230 batting average and a .324 on base percentage. Chase DeLauter has led the Guardians with seven home runs and 30 RBIs, while Jose Ramirez has added eight home runs and 24 RBIs. The projected starting pitcher for Cleveland is Gavin Williams, who is 6-3 with a 3.67 ERA and a 1.19 WHIP over 61.1 innings pitched this season. 

Why the Philadelphia Phillies will win

Why the Cleveland Guardians will win

Total Runs Facts

Philadelphia Phillies Player Prop Facts

Cleveland Guardians Player Prop Facts

Matchup/League Facts

Phillies vs Guardians Prediction 

Cleveland comes into this matchup on a nice winning streak and they have allowed three runs or fewer in five straight games. The Guardians are 15-12 on the road this year, while the Phillies are 13-14 at home. Philadelphia has been red hot over the last few weeks, but they did lose two out of three against the Reds. The Phillies are starting Sanchez, who has allowed zero earned runs in three straight starts, while Williams has allowed 5+ earned runs in three of his last five outings. Take the Phillies -1.5 here. 

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