In this article, we will formulate a Pirates vs Brewers Prediction for this MLB matchup on Friday, April 25th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
Milwaukee Brewers Preview
The Milwaukee Brewers have a 13-11 record this season and are sitting in the fifth place of the NL Central. They have a 7-5 home record and are coming off a 4-5 road loss against the Tigers. Their previous three games were a 2-5 road loss and a 12-4 road win against the Tigers, and a 3-5 road loss against the Marlins.
The Brewers have a .241 batting average this season, .342 OBP and .368 Slugging percentage. Milwaukee’s pitching staff has a 3.98 ERA and 1.33 WHIP. William Contreras is the team’s best hitter with a .302 batting average. Brice Turang leads the team in RBI with 18, and Gary Sanchez adds a team‑high 5 home runs.
Brandon Woodruff (R) is the projected starting pitcher for the Brewers, and he has a 2-0 record, 3.42 ERA and 0.93 WHIP.
Pittsburgh Pirates Preview
The Pittsburgh Pirates have a 14-11 record this season and are sitting in the fourth place of the NL Central. They have a 6-6 away record and are coming off a 1-6 road loss against the Rangers. Their previous three games were an 8-4 road win and a 1-5 road loss against the Rangers, and a 6-3 home win against the Rays.
The Pirates have a .247 batting average this season, .332 OBP and .386 Slugging percentage. Pittsburgh’s pitching staff has a 3.45 ERA and 1.29 WHIP. Ryan O’Hearn is the team’s best hitter with a .325 batting average. Oneil Cruz leads the team in RBI with 23, also adding a team‑high 8 home runs.
Paul Skenes (R) is the projected starting pitcher for the Pirates, and he has a 3-1 record, 3.27 ERA and 0.91 WHIP.
Pittsburgh Pirates @ Milwaukee Brewers Betting Trends: April 24, 2026
- Probable Starting Pitcher: Brandon Woodruff Record this season: 2-0 ERA: 3.42
- Home Record: 1-0
- Last 5 against Pirates: 2-1
Why the Milwaukee Brewers will win
- The Brewers have won each of their last six games as underdogs against NL Central opponents following a loss.
- The Pirates have lost each of their last six games against the Brewers following a loss.
- The Brewers have covered the run line in each of their last eight games against the Pirates.
- The Pirates have failed to cover the run line in each of their last seven games against the Brewers following a loss.
- The Pirates have trailed after 3 innings in each of their last five games at American Family Field.
- The Brewers have led after 5 innings in seven of their last eight games against the Pirates.
- The Brewers have won the first inning in three of their last four night games against the Pirates.
- Probable Starting Pitcher: Paul Skenes Record this season: 3-1 ERA: 3.27
- Road Record: 1-1
- Last 5 against Brewers: 1-2
Why the Pittsburgh Pirates will win
- The Pirates have won each of their last nine games following a loss.
- The Brewers have lost each of their last six games against National League opponents following a loss.
- The Pirates have covered the run line in each of their last nine games following a loss.
- The Brewers have failed to cover the run line in 11 of their last 12 home games against National League opponents after playing the previous day.
- The Pirates have led after 3 innings in five of their last six games against opponents that held a winning record.
- The Pirates have led after 5 innings in five of their last six games against opponents that held a winning record.
- The Pirates have won the first inning in four of their last five games.
Total Runs Facts
- Five of the Pirates’ last six road games after playing the previous day have gone OVER the total runs line.
- Four of the Brewers’ last five night games after playing the previous day have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Pirates’ last 11 games as road favorites against NL Central opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Brewers’ last five games against NL Central opponents.
Milwaukee Brewers Player Prop Facts
- Brandon Woodruff has recorded a win in each of his last four home appearances against opponents that held a winning record.
- Brandon Woodruff has recorded seven or more strikeouts in each of his last five home appearances against opponents that held a winning record.
- Andrew Vaughn has hit a home run in each of the Brewers’ last two home games against NL Central opponents.
- Christian Yelich has recorded at least one hit in each of his last 10 appearances against the Pirates.
- Garrett Mitchell ranks 6th amongst qualified players for On Base Percentage (.421) this season.
Pittsburgh Pirates Player Prop Facts
- Oneil Cruz has hit at least one home run in each of the Pirates’ last three games as road favorites.
- Oneil Cruz has recorded at least one hit in each of the Pirates’ last eight road games.
- Oneil Cruz ranks T2nd in the league in Steals (10) this season.
Matchup/League Facts
- The Brewers rank 1st in the league for steals this season (35).
- The Brewers rank T1st in the league for walks this season (119).
- The Pirates are one of only four teams in the league to rank top 10 in both steals and home runs this season.
- The Pirates rank T4th in the league for home runs allowed this season (19).
Pirates vs Brewers Prediction
The Brewers have won their last 8 meetings against the Pirates and have won their last four meetings in Milwaukee.
In this Pirates vs Brewers Prediction, the Pirates are coming as -135 road favorites. We got ourselves a pitching duel in this game, as Paul Skenes goes up against Brandon Woodruff. Skenes has just three earned runs in his last four starts and Woodruff has two earned runs in his last two starts. The Pirates have scored just one run in two of their last three games and the Brewers’ offense has been shaky lately. Runs will be at a premium today, so take the under 7 in this one.