Pirates vs Cardinals Prediction 8/27/25 MLB Picks Today

In this article, we will formulate a Pirates vs Cardinals Prediction for this MLB game on Wednesday, August 27th at the Busch Stadium in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 65-68 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 31-36 home record and are 68-57 in over/under They are coming off a 3-8 home defeat by the Pirates, and are 1-3 in their last 4 games. Over is 8-0-2 in their last 10 games and are playing the Athletics and the Reds next.


The Cardinals have a .248 batting average this season, .317 OBP and .384 Slugging percentage. St. Louis’ pitching staff has a 4.33 ERA and 1.31 WHIP. Alec Burleson leads the Cardinals with 123 hits, and he is the team’s best hitter with a .291 batting average. Wilson Contreras leads the team in RBI, with 73, adding a team-high 19 home runs.

Sonny Gray (R) is the projected starting pitcher for the Cardinals, and he has a 12-66 record, 4.33 ERA and 1.20 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 58-75 record this season and are sitting on the last place of the NL Central. They have a 19-45 road record, and are 55-73 in over/under. They are coming off an 8-3 road victory over the Cardinals, and are 5-1 in their last 6 games. They are playing the Red Sox and the Dodgers next.

The Pirates have a .235 batting average this season, .306 OBP and .353 slugging percentage. Pittsburgh’s pitching staff has a 3.95 ERA and 1.22 WHIP. Bryan Reynolds leads the Pirates with 122 hits, and a team-high 66 RBI. He is also the team’s best hitter with a .247 batting average, while Oneil Cruz leads the team in home runs, with 18.

Carmen Mlodzinski (R) is the projected starting pitcher for the Pirates, and he has a 3-7 record, 3.89 ERA and 1.30 WHIP.

Why the St. Louis Cardinals will win

Why the Pittsburgh Pirates will win

Total Runs Facts

Matchup/League Facts

Pirates vs Cardinals Prediction

The Pirates are 4-1 in their last 5 head-to-head meetings against the Cardinals, but the Cardinals are 4-1 in their last 5 home meetings against the Pirates. Over is 7-0 in their last 7 meetings.

In this Pirates vs Cardinals Prediction, the Cardinals are coming as -190 home favorites. The Cardinals are rightfully such big favorites, as they are putting Gray on the mound, who has 12 wins this season and has been stronger at home, with a 3.76 home ERA. His previous home start against the Pirates this season was a shutout. On the flip side, Mlodzinski has been struggling on the road, with a 5.10 ERA across 6 road starts, and the Pirates’ bats are dead last in the league in runs per game, so the edge goes to the home team. Take the St. Louis Cardinals in a bounce-back spot at home in this one.

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