Red Sox vs Athletics Prediction 9/16/25 MLB Picks Today

The Athletics and Boston Red Sox meet Tuesday in MLB action at Fenway Park. Here’s a Red Sox vs Athletics Prediction. This article will include a Red Sox vs Athletics Pick.

Athletics Betting Preview

The Athletics are 70-80 on the year and play the Pirates, Astros, and Royals next. The Athletics are batting .255 on the season, have a .321 OBP, and a .438 slugging percentage. The Athletics pitching staff has a 4.77 ERA and a 1.36 WHIP. Brent Rooker leads the Athletics with 158 hits and 85 RBI, while Tyler Soderstrom and Jacob Wilson have combined for 286 hits and 147 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 10-11 with a 4.28 ERA and 132 strikeouts this season. Springs is 0-3 with a 4.55 ERA and 38 strikeouts in his career against the Boston Red Sox.

Boston Red Sox Betting Preview

The Boston Red Sox are 82-68 on the year and play the Rays, Blue Jays, and Tigers next. The Boston Red Sox are batting .254 on the season, have a .324 OBP, and a .425 slugging percentage. The Boston Red Sox pitching staff has a 3.74 ERA and a 1.29 WHIP. Jarren Duran leads the Boston Red Sox with 148 hits and 80 RBI while Trevor Story and Ceddanne Rafaela have combined for 267 hits and 151 RBI.

Connelly Early gets the ball for the Boston Red Sox, and he is 1-0 with a 0.00 ERA and 11 strikeouts this season. This will be Early’s second career game against the Athletics.

Athletics @ Boston Red Sox Betting Trends: September 16, 2025

 

Why the Boston Red Sox will win

 

Why the Athletics will win

Total Runs Facts

Boston Red Sox Player Prop Facts

Athletics Player Prop Facts

Matchup/League Facts

Red Sox vs Athletics Prediction

The Athletics have put together some nice wins lately, but they’re still not a team I’m running to back with just two weeks left in the season. Springs also isn’t off to a great September, allowing 13 hits and 7 runs in 11 innings. The Red Sox need to take advantage of games like this in terms of playoff positioning, and Early just shutout the A’s through 5 innings while striking out 11. I’m sure the Athletics will have some sort of success seeing Early again, but I’m still siding with the Red Sox on Tuesday night.

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