Red Sox vs Cardinals Prediction 4/4/25 MLB Picks Today

In this article we will formulate a Red Sox vs Cardinals prediction for this MLB game on Friday, April 4th at Fenway Park in Boston, Massachusetts. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 3-4 this season after they won two out of three against Baltimore in their last series. Boston lost game one in the series by a score of 8-5, but they did win games two and three by scores of 3-0 and 8-4. In their last game, the Red Sox scored in five of the nine innings and were able to cruise to the win after pulling away in the seventh. Boston recorded 11 hits in the game and they were led by Bregman, who went 3-5 with one home run and three RBI’s in the win. The Red Sox started Houck, who allowed five hits and three earned runs over 4.0 innings of work, while Whitlock allowed one earned run and one hit over the final two innings. 


Prior to that series, the Red Sox lost three out of four against the Rangers by scores of 5-2, 1-4, 3-4, and 2-3. The Boston pitching staff has a 3.81 ERA with a 1.19 WHIP and a .258 opponent batting average, while their offense has scored 27 runs with a .229 batting average and a .303 on base percentage this season. Wilyer Abreu has led Boston with two home runs and six RBIs, while Kristian Campbell has added two home runs and four RBIs this year. The projected starting pitcher for Boston is Walker Buehler, who is 0-1 with an 8.31 ERA and a 1.62 WHIP over 4.1 innings pitched this year. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 4-2 this year after they lost two out of three against the Angels in their last series. St. Louis lost games one and two by scores of 5-4 and 9-7, but did win game three by a score of 12-5 to avoid the sweep. In game three, the Cardinals trailed 5-3 in the seventh inning, but they scored seven runs in the eighth to get the big win. St. Louis recorded 12 hits in the game and they were led by Herrera, who went 3-4 with three home runs and six RBIs in the win. The Cardinals started Gray, who allowed five hits and five earned runs over 6.0 innings, while Romero pitched the final 1.1 innings for the win. 

Prior to that series, the Cardinals swept the Twins by scores of 5-3, 5-1, and 9-2. The St. Louis pitching staff has a 3.47 ERA with a 0.86 WHIP and a .181 opponent batting average, while their offense has scored 42 runs with a .298 batting average and a .381 on base percentage this season. Ivan Herrera has led St. Louis with three home runs and eight RBIs, while Lars Nootbaar has added two home runs and five RBIs this year. The projected starting pitcher for St. Louis Erick Fedde, who is 1-0 with a 1.50 ERA and a 0.33 WHIP over 6.0 innings pitched this season. 

Why the Red Sox will beat the Cardinals

Why the Cardinals will beat the Red Sox

Total Runs Facts

Boston Red Sox Player Prop Facts

St. Louis Cardinals Player Prop Facts

Red Sox vs Cardinals Prediction 

St. Louis comes into this matchup with one of the higher scoring offenses in the MLB and they are hitting nearly .300 as a team right now. Boston did win their last two games against Baltimore, but they are starting Buehler, who was not good in his first outing. The Cardinals are going with Fedde on the mound, who pitched well last time out, but I think he is going to struggle against this Boston lineup at Fenway. Take the over here. 

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