Red Sox vs Cubs Prediction 9/25/26 MLB Picks Today

The Chicago Cubs and Boston Red Sox meet Friday in an MLB doubleheader at Fenway Park. Here’s a Red Sox vs. Cubs Prediction. This article will include a Red Sox vs. Cubs Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 88-71 on the year. The Chicago Cubs are batting .251 on the season, with a .339 OBP and a .429 slugging percentage. The Chicago Cubs’ pitching staff has a 4.15 ERA and a 1.26 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 173 hits and 107 RBI, while Alex Bregman and Nico Hoerner have combined for 320 hits and 161 RBI.

Clay Holmes and David Peterson get the ball for the Chicago Cubs.

Boston Red Sox Betting Preview

The Boston Red Sox are 85-74 on the year. The Boston Red Sox are batting .246 on the season, have a .319 OBP, and have a .399 slugging percentage. The Boston Red Sox pitching staff has a 3.55 ERA and a 1.23 WHIP. Ceddanne Rafaela leads the Boston Red Sox with 152 hits and 70 RBI, while Wilyer Abreu and Caleb Durbin have combined for 272 hits and 138 RBI.

Alec Gamboa and Brayan Bello get the ball for the Boston Red Sox.

Why the Boston Red Sox will win

Why the Chicago Cubs will win

Total Runs Facts

Boston Red Sox Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Red Sox vs Cubs Prediction

Game 1 Prediction: I’m not a fan of openers, but the Red Sox have the edge with the quick start at home. Also, Holmes has been a mess lately, allowing 14 hits and 16 earned runs in his last 15.1 innings. Holmes also has a 4.44 ERA through 50.2 innings on the road compared to a 1.94 ERA in 46.1 innings at home. I’ll roll with the Red Sox at home in game 1.

Game 2 Prediction: Peterson has been hittable all season, and that includes allowing 19 hits and 9 runs in his last 20 innings. Peterson has a control issue and has walked 14 batters in his last 25 innings. Bello has found his form lately, allowing 9 hits and 1 run in his last 14.2 innings. It’s hard to sweep a doubleheader, but I like the Red Sox in both games on Friday.

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