Red Sox vs Rays Prediction 9/19/25 MLB Picks Today

In this article, we will formulate a Red Sox vs Rays Prediction for this MLB game on Friday, September 19th at the George M. Steinbrenner Field in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 75-78 record this season and are sitting on the 4th place of the AL East. The Rays have a 40-38 home record and are 66-77 in over/under. They are coming off a 4-0 home victory over the Blue Jays, and have back-to-back wins. Under is 3-1 in their last 4 games and are playing the Orioles and the Blue Jays next.

The Rays have a .252 batting average this season, .314 OBP and .403 slugging percentage. Tampa’s pitching staff has a 3.83 ERA and 1.20 WHIP.  Yandy Diaz leads the Rays with 167 hits, and he is the team’s best hitter with .297 batting average. Junior Caminero leads the team in RBI, with 108 and in home runs, with 44.

Drew Rasmussen (R) is the projected starting pitcher for the Rays, and he has a 10-5 record, 2.74 ERA and 1.00 WHIP.

Boston Red Sox Preview

The Boston Red Sox have an 83-70 record this season and are sitting on the third place of the AL East. The Red Sox have a 37-38 road record and are 72-77 in over/under. They are coming off a 3-5 home defeat by the A’s, but are 2-5 in their last 7 games. They are 6-2-1 to the under in their last 9 games and are playing the Tigers and the Blue Jays next.

The Red Sox have a .253 batting average this season, .323 OBP and .423 slugging percentage. Boston’s pitching staff has a 3.73 ERA and 1.29 WHIP. Trevor Story leads the Red Sox with 154 hits, while is the team’s best hitter, with a .268 batting average. He also leads the team in RBI, with 93, adding a team-high 25 home runs.

Garrett Crochet (R) is the projected starting pitcher for the Red Sox, and he has a 16-5 record, 2.63 ERA and 1.05 WHIP.

Boston Red Sox @ Tampa Bay Rays Betting Trends: September 19, 2025

 

Why the Tampa Bay Rays will win

 

Why the Boston Red Sox will win

Total Runs Facts

Tampa Bay Rays Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Red Sox vs Rays Prediction

The Red Sox are 8-1 in their last 9 head-to-head meetings against the Rays, and are 2-1 in their last 3 visits in Tampa Bay. Under is 5-0-1 in their last 6 meetings.

In this Red Sox vs Rays Prediction, the Red Sox are coming as -130 road favorites. Crochet faces off with Rasmussen in this pitcher’s duel as both have been excellent this season and have even better home/away splits. Rasmussen has a 2.60 home ERA and Crochet a 2.29 road ERA. Boston has the second-bet bullpen ERA in baseball, while Tampa has been terrible against lefties, with their batting average dropping from .252 to .235 against left-handed pitching, scoring just 3.6 runs per game. I expect Crochet to be unhittable in this one, so take the Red Sox to win on the road.

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