Reds vs Cardinals Prediction 4/28/25 MLB Picks Today

The St. Louis Cardinals and Cincinnati Reds meet Monday in MLB action at Great American Ball Park. Here’s a Reds vs Cardinals Prediction. This article will include a Reds vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 12-16 on the year and play the Mets, Pirates, and Nationals next. The St. Louis Cardinals are batting .265 on the season, have a .336 OBP, and a .401 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.36 ERA and a 1.25 WHIP. Brendan Donovan leads the St. Louis Cardinals with 37 hits and 16 RBI, while Lars Nootbaar and Nolan Arenado have combined for 53 hits and 29 RBI.

Andre Pallante gets the ball for the St. Louis Cardinals, and he is 2-1 with a 4.05 ERA and 16 strikeouts this season. Pallante is 5-1 with a 1.83 ERA and 32 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 15-13 on the year and play the Nationals, Braves, and Astros next. The Cincinnati Reds are batting .254 on the season, have a .333 OBP, and a .404 slugging percentage. The Cincinnati Reds pitching staff has a 3.46 ERA and a 1.10 WHIP. TJ Friedl leads the Cincinnati Reds with 32 hits and 12 RBI, while Elly De La Cruz and Gavin Lux have combined for 59 hits and 37 RBI.

Nick Martinez gets the ball for the Cincinnati Reds, and he is 0-3 with a 5.40 ERA and 23 strikeouts this season. Martinez is 0-2 with a 3.72 ERA and 6 strikeouts in his career against the St. Louis Cardinals.

Why the Cincinnati Reds will win

Why the St. Louis Cardinals will win

Cincinnati Reds Player Prop Facts

St. Louis Cardinals Player Prop Facts

Reds vs Cardinals Prediction

The Reds are going to get some love here, as they’ve won four straight games. Let’s pump the brakes, however, as those wins came against the Marlins and Rockies. I’m not ready to say the Reds have figured things out. Martinez has been hittable all year, as he’s allowed 28 hits and 16 earned runs in 26.2 innings. Pallante has had his issues as well, but they’re not nearly as shaky as Martinez’s. Also, Pallante has owned the Reds over his career, which includes holding current batters to a .188 batting average and 13 strikeouts in 64 at-bats. I need to see more from the Reds. I’ll take the plus money with the Cardinals on Monday night.

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