Reds vs Cardinals Prediction 8/29/25 MLB Picks Today

The St. Louis Cardinals and Cincinnati Reds meet Friday in MLB action at Great American Ball Park. Here’s a Reds vs Cardinals Prediction. This article will include a Reds vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 66-69 on the year and play the Athletics, Giants, and Mariners next. The St. Louis Cardinals are batting .248 on the season, have a .316 OBP, and a .383 slugging percentage. The St. Louis Cardinals pitching staff has a 4.28 ERA and a 1.30 WHIP. Alec Burleson leads the St. Louis Cardinals with 123 hits and 60 RBI, while Brendan Donovan and Masyn Winn have combined for 235 hits and 92 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 6-11 with a 4.27 ERA and 98 strikeouts this season. Liberatore is 1-1 with a 2.53 ERA and 9 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 68-66 on the year and play the Blue Jays, Mets, and Padres next. The Cincinnati Reds are batting .246 on the season, have a .316 OBP, and a .388 slugging percentage. The Cincinnati Reds pitching staff has a 3.84 ERA and a 1.24 WHIP. Elly De La Cruz leads the Cincinnati Reds with 142 hits and 77 RBI while TJ Friedl and Spencer Steer have combined for 230 hits and 103 RBI.

Zack Littell gets the ball for the Cincinnati Reds, and he is 9-8 with a 3.62 ERA and 106 strikeouts this season. Littell is 0-2 with a 7.04 ERA and 10 strikeouts in his career against the St. Louis Cardinals.

Why the Cincinnati Reds will win

Why the St. Louis Cardinals will win

Cincinnati Reds Player Prop Facts

St. Louis Cardinals Player Prop Facts

Reds vs Cardinals Prediction

I’m not excited to get involved in a game between two struggling teams. I’m looking at the over instead. Liberatore has allowed 22 hits and 13 earned runs in his last 21.2 innings. Liberatore has allowed a homer in each of his last four starts. Littell has allowed eight earned runs in his last 13.2 innings. Littell has walked four batters in his last nine innings. Give me the over on Friday between the Cards and Reds.

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