Reds vs Diamondbacks Prediction 8/22/26 MLB Picks Today

In this article, we will formulate a Reds vs Diamondbacks Prediction for this MLB matchup on Saturday, August 22nd in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 68-61 record this season and are sitting in the 3rd place of the NL West. They have a 37-27 home record and are coming off a 9-0 home win against the Reds. They will face the Cubs and the Giants next.

The Arizona Diamondbacks have a .244 batting average this season, .318 OBP and .399 Slugging percentage. Arizona’s pitching staff has a 4.14 ERA and 1.28 WHIP. Gabriel Moreno is the Diamondbacks’ best hitter with a .308 batting average. Ketel Marte leads the team in RBI with 67, while also adding a team-high 21 home runs.

Michael Soroka (R) is the projected starting pitcher for the Diamondbacks, and he has a 8-3 record, 2.93 ERA and 1.11 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 61-68 record this season and are sitting in the 5th place of the NL Central. They have a 29-32 road record and are coming off a 0-9 road loss against the Diamondbacks. They will face the Giants and the Cubs next.

The Cincinnati Reds have a .225 batting average this season, .305 OBP and .389 Slugging percentage. Cincinnati’s pitching staff has a 4.51 ERA and 1.41 WHIP. Sal Stewart is the Reds’ best hitter with a .259 batting average, while also leading the team in RBI with 96 and adding a team-high 27 home runs.

Rhett Lowder (R) is the projected starting pitcher for the Reds, and he has a 4-8 record, 5.17 ERA and 1.49 WHIP.

Cincinnati Reds @ Arizona Diamondbacks Betting Trends: August 22, 2026

 

Why the Arizona Diamondbacks will win

 

Why the Cincinnati Reds will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Reds vs Diamondbacks Prediction

The Diamondbacks are 3-1 in their last 4 meetings against the Reds and are 3-1 in their last 4 meetings in Arizona.

In this Reds vs Diamondbacks Prediction, the Diamondbacks are coming as -160 home favorites. I like the Dbacks at home in this one, as they have a big pitching edge with Michael Soroka going up against Rhett Lowder. Soroka has given up just two runs in his two starts after his injury and has been even better at home with a 1.88 ERA. On the flip side, Lowder has been terrible on the road with a 7.23 ERA and in their last 10 game, the Dbacks have both a better offense and a better bullpen ERA. Take the Dbacks at home in this one.

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