Reds vs Diamondbacks Prediction 6/6/25 MLB Picks Today

The Arizona Diamondbacks and Cincinnati Reds meet Friday in MLB action at Great American Ball Park. Here’s a Reds vs Diamondbacks Prediction. This article will include a Reds vs Diamondbacks Pick.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 31-31 on the year and play the Mariners, Padres, and Blue Jays next. The Arizona Diamondbacks are batting .255 on the season, have a .333 OBP, and a .448 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.76 ERA and a 1.33 WHIP. Josh Naylor leads the Arizona Diamondbacks with 67 hits and 39 RBI, while Corbin Carroll and Geraldo Perdomo have combined for 125 hits and 81 RBI.

Eduardo Rodriguez gets the ball for the Arizona Diamondbacks, and he is 1-3 with a 7.05 ERA and 52 strikeouts this season. Rodriguez is 1-1 with a 2.77 ERA and 11 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 30-33 on the year and play the Guardians, Tigers, and Twins next. The Cincinnati Reds are batting .243 on the season, have a .318 OBP, and a .391 slugging percentage. The Cincinnati Reds pitching staff has a 3.80 ERA and a 1.20 WHIP. TJ Friedl leads the Cincinnati Reds with 68 hits and 20 RBI, while Elly De La Cruz and Gavin Lux have combined for 114 hits and 65 RBI.

Nick Lodolo gets the ball for the Cincinnati Reds, and he is 4-4 with a 3.10 ERA and 60 strikeouts this season. This will be Lodolo’s first career game against the Arizona Diamondbacks.

Why the Cincinnati Reds will win

• The underdogs have won seven of the Diamondbacks’ last eight games.
• The Diamondbacks have lost six of their last seven games as favorites following a win.
• The Diamondbacks have failed to cover the run line in each of their last six games as road favorites.
• The underdogs have covered the run line in seven of the Diamondbacks’ last eight games.
• The Reds have led after 5 innings in four of their last five games as home underdogs against National League opponents.
• The Reds have led after 3 innings in four of their last five games as home underdogs against National League opponents.
• The Reds have won the first inning in each of their last three games as home underdogs against National League opponents.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last seven games at Great American Ball Park following a win.
• The Reds have lost seven of their last eight games against the Diamondbacks following a home loss.
• The Diamondbacks have covered the run line in each of their last 10 road games against the Reds following a win.
• The Reds have failed to cover the run line in nine of their last 10 home games against the Diamondbacks following a loss.
• The Diamondbacks have led after 5 innings in each of their last four road night games.
• The Diamondbacks have led after 3 innings in each of their last eight games against the Reds.

Cincinnati Reds Player Prop Facts

• Tyler Stephenson has hit a home run in each of his last two appearances after not playing the previous day.
• Elly De La Cruz has scored at least one run in seven of the Reds’ last eight games as underdogs.
• Nick Lodolo has recorded six or more strikeouts in nine of his last 10 appearances with the Reds as home underdogs.
• TJ Friedl has recorded at least one hit in each of the Reds’ last eight night games.
• TJ Friedl has recorded at least one Single in each of the Reds’ last seven night games.
• Gavin Lux has recorded a Double in each of his last three appearances against the Diamondbacks.
• Nick Lodolo has recorded a win in each of his last three appearances against NL West opponents.
• Garrett Hampson has recorded at least one RBI in four of his last five appearances with his team as an underdog against the Diamondbacks.
• Elly De La Cruz ranks T5th in the league in Steals (19) this season.

Arizona Diamondbacks Player Prop Facts

• Eugenio Suarez has hit at least one home run in four of the Diamondbacks’ last five night games against NL Central opponents that held a losing record.
• Ketel Marte has recorded at least one RBI in each of his last four appearances with the Diamondbacks as road favorites against NL Central opponents.
• Ketel Marte has scored at least one run in each of his last six road appearances against NL Central opponents.
• Eduardo Rodriguez has recorded five or more strikeouts in each of his last 18 appearances against opponents that held a losing record.
• Lourdes Gurriel Jr. has recorded at least one Single in each of his last eight appearances against NL Central opponents.
• Eugenio Suarez has recorded a Double in three of the Diamondbacks’ last four road games against NL opponents.
• Eduardo Rodriguez has recorded a win in each of his last nine Friday appearances against teams that held a losing record.
• Josh Naylor has recorded at least one hit in each of his last 13 appearances against NL Central opponents that held a losing record.
• Corbin Carroll ranks 5th in the league in Home Runs (18) this season.

Reds vs Diamondbacks Prediction

I’m not thrilled to back the Reds, who have underachieved all year, but I can’t get behind the Diamondbacks with Rodriguez on the mound. Rodriguez has been a disaster this season with his 7.05 ERA and 1.70 WHIP, and he hasn’t pitched in three weeks due to a shoulder injury. Lodolo has been solid this season with a 3.10 ERA and 1.11 WHIP, and he just shut out the Cubs on the road through six innings. The Reds are at home with the clear pitching advantage. There are no excuses. Give me the Reds in a much-needed victory.