Reds vs Guardians Prediction 7/28/26 MLB Picks Today

In this article we will formulate a Reds vs Guardians prediction for this MLB game on Tuesday, July 28th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 49-55 this year after they won two out of three against the Cardinals by scores of 4-2, 0-7, and 5-3. In game three, Cincinnati tied the game at two in the fifth inning and they scored three runs in the 10th to secure the win. The Reds recorded 10 hits and they committed two errors in the game, while they were led by Lowe, who went 3-5 with two RBIs. Abbott allowed three hits and two earned runs over 6.0 innings, while Burke got the win and Garcia picked up the save. Prior to that series, Cincinnati won two out of three against the Mariners and two out of three against the Rockies. 

This season, Cincinnati has a 4.52 ERA with a 1.42 WHIP and a .246 opponent batting average, while they have scored 432 runs with a .230 batting average and a .308 on base percentage. Sal Stewart has led the Reds with 21 home runs and 76 RBIs, while Elly De La Cruz has added 18 home runs and 47 RBIs. The projected starting pitcher for Cincinnati in game one is Chase Burns, who is 12-1 with a 2.42 ERA and a 1.11 WHIP over 107.2 innings pitched this year. The projected starting pitcher for game two is Brady Singer, who is 5-9 with a 4.53 ERA and a 1.38 WHIP over 103.1 innings pitched. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 54-53 this season after they lost all three against the Rays by scores of 3-11, 0-3, and 0-1. In game three, Cleveland got a great pitching performance, but their offense produced nothing in the shutout loss. The Guardians recorded one hit and they were led by Kwan, who went 1-4 in the game. Messick allowed six hits and one earned run over 7.2 innings, while Holderman threw 0.1 innings in relief. Prior to that series, Cleveland split four games with the Twins and lost two out of three against the Pirates. 

This season, Cleveland has a 3.75 ERA with a 1.27 WHIP and a .239 opponent batting average, while they have scored 420 runs with a .230 batting average and a .309 on base percentage. Chase DeLauter has led the Guardians with 11 home runs and 50 RBIs, while Angel Martinez has added 11 home runs and 33 RBIs. The projected starting pitcher for Cleveland in game one is Slade Cecconi, who is 4-7 with a 4.60 ERA and a 1.45 WHIP over 103.2 innings pitched this season. The projected starter for game two is Gavin Williams, who is 10-5 with a 3.78 ERA and a 1.10 WHIP over 126.1 innings pitched.

Why the Cincinnati Reds will win

Why the Cleveland Guardians will win

Total Runs Facts

Cincinnati Reds Player Prop Facts

Cleveland Guardians Player Prop Facts

Matchup/League Facts

Reds vs Guardians Prediction 

Cleveland comes into this matchup on a five game losing streak and they have scored one run or fewer in three of their last four games. The Guardians are 27-27 on the road this year, while the Reds are 22-28 at home. Cincinnati has won four of their last five games and they have allowed three runs or fewer in all four of those wins. In game one, I think Cincinnati has the edge with Burns on the mound, so I will take Reds -1.5. In game two, I will take Cleveland to win with Williams pitching. 

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