Reds vs Mariners Prediction 7/21/26 MLB Picks Today

In this article, we will formulate a Reds vs Mariners Prediction for this MLB matchup on Tuesday, July 21st in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 51-50 record this season and are sitting in the 1st place of the AL West. They have a 30-21 home record and are coming off an 8-0 home win against the Reds. They will face the Rangers and the Dodgers next.

The Seattle Mariners have a .230 batting average this season, .310 OBP and .378 Slugging percentage. Seattle’s pitching staff has a 3.57 ERA and 1.17 WHIP. Randy Arozarena is the team’s best hitter with a .284 batting average. Cole Young leads the team in RBI with 48, while Luke Raley adds a team-high 15 home runs.

Luis Castillo (R) is the projected starting pitcher for the Seattle Mariners, and he has a 3-8 record, 4.93 ERA and 1.37 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 45-54 record this season and are sitting in the 5th place of the NL Central. They have a 23-26 away record and are coming off a 0-8 road loss against the Mariners. They will face the Cardinals and the Guardians next.

The Cincinnati Reds have a .230 batting average this season, .310 OBP and .399 Slugging percentage. Cincinnati’s pitching staff has a 4.60 ERA and 1.44 WHIP. Elly De La Cruz is the team’s best hitter with a .279 batting average. Sal Stewart leads the team in RBI with 70, adding a team-high 20 home runs.

Chase Burns (R) is the projected starting pitcher for the Cincinnati Reds, and he has a 11-1 record, 2.54 ERA and 1.11 WHIP.

Cincinnati Reds @ Seattle Mariners Betting Trends: July 21, 2026

 

Why the Seattle Mariners will win

 

Why the Cincinnati Reds will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Reds vs Mariners Prediction

The Mariners are 7-1 in their last 8 meetings against the Reds, having won their last four meetings in Seattle.

In this Reds vs Mariners Prediction, the Mariners are coming as -115 home favorites. I like the Reds in a bounce-back spot today with their ace on the mound in Chase Burns. He has not been himself lately with 10 earned runs across his last three starts, but he had to face two of the four best offenses in baseball. He has a 5-0 record and 2.75 ERA on the road, while Castillo has been shaky at best this season for the Mariners and has a 1-3 record and 5.26 ERA at home. On top of that, Seattle’s offense has been struggling in their last 10 games and has been even weaker against right-handed pitching. Take the Reds to win this one.

 

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