Reds vs Padres Prediction 6/29/25 MLB Picks Today

The San Diego Padres and Cincinnati Reds meet Sunday in MLB action at Great American Ball Park. Here’s a Reds vs Padres Prediction. This article will include a Reds vs Padres Pick.

San Diego Padres Betting Preview

The San Diego Padres are 45-37 on the year and play the Phillies, Rangers, and Diamondbacks next. The San Diego Padres are batting .247 on the season, have a .315 OBP, and a .379 slugging percentage. The San Diego Padres pitching staff has a 3.65 ERA and a 1.22 WHIP. Manny Machado leads the San Diego Padres with 93 hits and 47 RBI, while Luis Arraez and Fernando Tatis Jr. have combined for 167 hits and 68 RBI.

Stephen Kolek gets the ball for the San Diego Padres, and he is 3-3 with a 3.95 ERA and 42 strikeouts this season. Kolek is 0-0 with a 0.00 ERA and 0 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 43-40 on the year and play the Red Sox, Phillies, and Marlins next. The Cincinnati Reds are batting .247 on the season, have a .320 OBP, and a .402 slugging percentage. The Cincinnati Reds pitching staff has a 3.84 ERA and a 1.22 WHIP. Elly De La Cruz leads the Cincinnati Reds with 88 hits and 56 RBI while TJ Friedl and Spencer Steer have combined for 157 hits and 62 RBI.

Nick Lodolo gets the ball for the Cincinnati Reds, and he is 5-5 with a 3.63 ERA and 80 strikeouts this season. Lodolo is 1-1 with a 3.00 ERA and 19 strikeouts in his career against the San Diego Padres.

Why the Cincinnati Reds will win

• The Reds have won eight of their last nine games against NL West opponents following a loss.
• The Padres have lost seven of their last eight games against National League opponents following a win.
• The Padres have failed to cover the run line in each of their last seven games following a win.
• The Reds have covered the run line in seven of their last eight day games following a loss.
• The Reds have led after 5 innings in each of their last four games against NL West opponents that held a winning record.
• The Reds have won the first inning in each of their last four games as favorites.
• The Reds have led after 3 innings in each of their last four games against NL West opponents that held a winning record.

Why the San Diego Padres will win

• The Padres have won each of their last seven day games against NL Central opponents.
• The Reds have lost four of their last five games as home favorites against National League opponents.
• The Padres have covered the run line in each of their last eight games as underdogs against NL Central opponents.
• The Reds have failed to cover the run line in nine of their last 10 day games against the Padres following a loss.
• The Padres have led after 3 innings in three of their last four games as underdogs against National League opponents.

Cincinnati Reds Player Prop Facts

• Tyler Stephenson has hit at least one home run in four of his last six appearances with the Reds as favorites against NL West opponents.
• Jose Trevino has recorded at least one Double in each of his last three appearances against NL opponents that held a winning record.
• Nick Lodolo has recorded a win in three of his last four appearances against NL West opponents.
• Nick Lodolo has recorded five or more strikeouts in each of his last four appearances against opponents that held a winning record.
• Spencer Steer has recorded at least one hit in each of his last eight home appearances against NL West opponents that held a winning record.
• Elly De La Cruz ranks T4th in the league in Steals (22) this season.

San Diego Padres Player Prop Facts

• Gavin Sheets has hit a home run in each of his last two appearances with his team as a road underdog against the Reds.
• Jose Iglesias has recorded at least one hit in each of his last 13 appearances in day games against NL Central teams that held a winning record.
• Manny Machado ranks T8th in the league in Hits (93) this season.

Reds vs Padres Prediction

The Padres have cooled off a lot over the last few weeks, but I’m rolling with them in this spot. Kolek has been the more consistent pitcher this season, which includes allowing 24 hits and 11 earned runs in his last 26.1 innings. In 42.1 home innings, Kolek has a 2.13 ERA and .233 allowed batting average. Lodolo has allowed 19 hits and 12 runs in his last 19.2 innings. In 42.2 home innings, Lodolo has a 5.06 ERA and .273 allowed batting average. The Padres have the edge on the mound, so that’s where I’ll lean on Sunday.