San Diego Padres vs. Chicago Cubs Prediction 6-4-23 MLB Picks

San Diego Padres vs. Chicago Cubs Prediction 6-4-23 MLB Picks player photo
Credit: USA Today Sports

The Chicago Cubs and the San Diego Padres meet in MLB action from Petco Park on Sunday afternoon. Let’s dive into the odds, starting pitching matchup and make a prediction for this game.


The Padres are -115 home favorites while the Cubs are -105 road underdogs. The total for this game is set at 8.5 runs.

Starting Pitching Matchup

Marcus Stroman will start for the Cubs and is 5-4 with a 2.59 ERA and 62 strikeouts this season. Ryan Weathers will start for the Padres and is 1-3 with a 4.28 ERA and 22 strikeouts this season.


Chicago is 16-35 in their last 51 Sunday games and 10-23 in their last 33 games against the NL West while the over is 8-2 in their last 10 road games. San Diego is 1-5 in their last 6 home games while the under is 7-1 in their last 8 games against the NL Central.


I’m leaning towards the Cubs here. I’m not about to lay this kind of price with the Padres with Ryan Weathers as my starting pitcher and while Stroman’s been better at home, his road ERA hasn’t been all that bad just a hair over three. Stroman’s also looked far better in a lot of his recent starts and I think he delivers another solid outing here to get the Cubs the win on Sunday.

Chris Ruffolo's Free Pick:Chicago Cubs -105