The Cincinnati Reds and the San Francisco Giants meet Wednesday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. San Francisco Giants prediction.
Starting Pitching Matchup
The Cincinnati Reds will send out Nick Lodolo for the start in this one and Lodolo is 3-3 with a 5.04 ERA and 59 strikeouts this season. Landen Roupp will start for the Giants and is 7-13 with a 4.34 ERA and 130 strikeouts this season.
Cincinnati Reds Recap
The Cincinnati Reds come into this game looking to bounce back from a 3-1 loss at the hands of the San Francisco Giants last time out to sit at 62-71 on the year. After this series, the Reds will head on the road again for a series against the Chicago Cubs.
Reds Lose 8 Of Last 11
Entering Tuesday, Elly De La Cruz has 117 hits with 21 doubles, 5 triples, 21 home runs and 58 RBIs while Sal Stewart has 137 hits with 24 doubles, 27 home runs and 98 RBIs. Spencer Steer has 81 hits with 14 doubles, 16 home runs and 40 RBIs and Matt McLain has 68 hits with 17 doubles, 13 home runs and 35 RBIs. JJ Bleday’s added 81 hits with 14 doubles, 21 home runs and 51 RBIs as well on the year.
San Francisco Giants Recap
The San Francisco Giants will be looking to add on to their win over the Reds from Tuesday to sit at 54-78 on the year. After this series, the Giants will take on the Arizona Diamondbacks in a series at home.
Giants Pick Up Back-To-Back Ws
Going into Tuesday, Willy Adames has 107 hits with 25 doubles, 21 home runs and 51 RBIs along with 139 strikeouts. Matt Chapman has 72 hits with 18 doubles, a triple, 7 home runs and 42 RBIs and Jung Hoo Lee has 132 hits with 27 doubles, 4 triples, 9 home runs and 47 RBIs. Rafael Devers also has 120 hits with 31 doubles, 27 home runs and 73 RBIs but also has 144 strikeouts this season.
Cincinnati Reds @ San Francisco Giants Betting Trends: August 26, 2026
- Probable Starting Pitcher: Landen Roupp Record this season: 7-13 ERA: 4.34
- Home Record: 3-7
- Last 5 against Reds: 1-1
Why the San Francisco Giants will win
- The home team has won each of the Giants’ last six games.
- The Reds have lost seven of their last eight road games against NL opponents.
- The Reds have failed to cover the run line each of their last nine games against teams that held a losing record.
- The Giants have covered the run line in seven of their last eight day games against NL Central opponents.
- The Reds have trailed after 5 innings in each of their last six games against NL opponents that held a losing record.
- The Giants have won the first inning in each of their last four games.
- The Giants have led after 3 innings in each of their last four games.
- Probable Starting Pitcher: Nick Lodolo Record this season: 3-3 ERA: 5.04
- Road Record: 1-1
- Last 5 against Giants: 2-1
Why the Cincinnati Reds will win
- The Reds have won each of their last nine day games against NL West opponents following a loss.
- The Giants have lost eight of their last 10 games as favorites against NL opponents following a win.
- The Giants have failed to cover the run line in each of their last seven day games against NL Central opponents following a home win.
- The Reds have covered the run line in seven of their last eight day games against NL West opponents following a road loss.
- The Reds have led after 5 innings in three of their last four day games against NL West opponents.
- The Reds have led after 3 innings in three of their last four day games against NL West opponents.
Total Runs Facts
- Each of the Giants’ last five day games as favorites have gone OVER the total runs line.
- Four of the Reds’ last five day games against NL opponents have gone UNDER the total runs line.
- There has been at least one run scored in the first inning in nine of the Reds’ last 10 games against NL West opponents.
- There has been no run scored during the first inning in eight of Landen Roupp’s last nine home appearances as a starter.
San Francisco Giants Player Prop Facts
- Rafael Devers has hit a home run in four of the Giants’ last five games against NL Central opponents that held a losing record.
- Landen Roupp has recorded six or more strikeouts in four of his last five appearances against NL opponents that held a losing record.
- Drew Gilbert has recorded at least one hit in each of his last nine appearances with the Giants as home favorites.
Cincinnati Reds Player Prop Facts
- Sal Stewart has hit at least one home run in three of the Reds’ last five games against the Giants.
- Nick Lodolo has recorded a win in four of his last five road appearances against NL opponents that held a losing record.
- Nick Lodolo has recorded five or more strikeouts in each of his last six road appearances against opponents that held a losing record.
- Elly De La Cruz has recorded at least one hit in each of the Reds’ last 14 road games against NL West opponents that held a losing record.
Matchup/League Facts
- The Giants rank 30th in the league for walks this season (348).
- The Giants rank 1st in the league for home runs allowed this season (120).
- The Reds rank 30th in the league for batting average this season (.226).
- The Reds rank 30th in the league for on-base percentage this season (.305).
Cincinnati Reds vs. San Francisco Giants Prediction
I’m on the Giants here. Not often am I backing hte Giants with how poor and inconsistent their offense has been but the Reds are the team in this series with an offense that’s disappeared and I don’t think that changes with Roupp going out as one of San Francisco’s better starting options this season. I think San Francisco completes the sweep here so give me the Giants.