Cardinals vs Cubs Prediction 8/10/25 MLB Picks Today

The Chicago Cubs and the St. Louis Cardinals meet Sunday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cardinals vs Cubs Prediction.

Starting Pitching Matchup

The Chicago Cubs will send out Shota Imanaga for the start here and Imanaga is 8-4 with a 3.12 ERA and 70 strikeouts this season. In his career, Imanaga is 2-0 with a 2.41 ERA and 16 strikeouts against the Cardinals. Sonny Gray will get the nod for the Cardinals here and is 10-5 with a 4.21 ERA and 141 strikeouts this season. In his last five starts against the Cubs, Gray is 1-1 with a 2.45 ERA and 40 strikeouts.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to add on to their 9-1 win over the Cardinals from Saturday’s matchup to sit at 67-49 on the year. After this series, the Cubs will head on the road for a series against the Toronto Blue Jays.

Cubs Alternate Wins & Losses In 4 Straight

Ian Happ has 93 hits with 19 doubles, 16 home runs and 54 RBIs. Kyle Tucker has 111 hits including 21 doubles, 4 triples, 18 home runs and 61 RBIs while Seiya Suzuki also has 107 hits with 25 doubles and 27 home runs and 84 RBIs of his own. Pete Crow-Armstrong also has contributed 115 hits, 31 doubles, 4 triples, 27 home runs and 78 RBIs as well this season. Dansby Swanson has added 18 home runs and 55 RBIs, while also having 130 strikeouts and Suzuki has 127 strikeouts so far this season. Crow-Armstrong also has a team-high 29 stolen bases while Nico Hoerner has 19 stolen bases this season. Tucker’s also added 23 stolen bases while Michael Busch has also chipped in 15 doubles, 3 triples, 21 home runs and 61 RBIs this season.

Why the Chicago Cubs will win

Chicago Cubs Player Prop Facts

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to rebound from their loss at the hands of the Cubs on Saturday to fall to 59-59 on the year. After this series, the Cardinals will play host to the Colorado Rockies for a series.

Cardinals Looking For Consistency Of Their Own

Brendan Donovan has a team-high 115 hits along with 24 doubles, 9 home runs and 43 RBIs while Lars Nootbaar has 80 hits with 12 home runs, 40 RBIs, 16 doubles and 4 stolen bases. Nolan Arenado also has 85 hits with 15 doubles, 10 home runs and 43 RBIs of his own and Victor Scott II has 75 hits with 13 doubles, a triple, 33 RBIs and a team-high 29 stolen bases. Willson Contreras has also chipped in 103 hits with 29 doubles, 16 home runs and 64 RBIs of his own as well this season. Masyn Winn’s added 106 hits with 24 doubles, 8 home runs and 42 RBIs and Alec Burleson’s added 100 hits with 19 doubles, 14 home runs and 50 RBIs.

Why the St. Louis Cardinals will win

St. Louis Cardinals Player Prop Facts

Total Runs Facts

Cardinals vs Cubs Prediction

I’m on the Cubs here. I think the starters could cancel out here, but I just don’t trust this Cardinals team offensively. Furthermore, I think Imanaga’s not only the slightly better starter, but I think the Cubs’ bullpen can hold it down, and I trust the Cubs batting order more as well here. Give me the Cubs in this one.

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