Toronto Blue Jays vs Cincinnati Reds Prediction 9/25/26 MLB Picks Today

The Cincinnati Reds and the Toronto Blue Jays meet Friday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

The Cincinnati Reds will send out Nick Lodolo for the start and Lodolo is 3-6 with a 5.04 ERA and 80 strikeouts this season. The Toronto Blue Jays did not have a starting pitcher announced at the time that this article was posted.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to add on to their 7-6 win over Atlanta last time out to sit at 74-85 this season.

Reds Alternate Wins & Losses In 4 Straight

Sal Stewart leads the Reds across the board in hits, home runs, and RBIs with a team-high 162 hits, 32 home runs, and 110 RBIs while adding 25 doubles so far this season. Elly De La Cruz has added 156 hits with 29 doubles, 5 triples, 30 home runs, and 77 RBIs, while JJ Bleday has logged 98 hits with 16 doubles, 2 triples, 23 home runs, and 57 RBIs on the year. Spencer Steer has contributed 81 hits with 14 doubles, 16 home runs, and 40 RBIs. Matt McLain has chipped in 81 hits with 18 doubles, a triple, 15 home runs, and 40 RBIs for Cincinnati up to this point in the season.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to rebound from a 4-2 loss at the hands of the Orioles last time out to sit at 77-82 this season.

Blue Jays Drop 3 Straight & 7 Of Last 9

Ernie Clement leads the Blue Jays with a team-high 153 hits while adding 33 doubles, a triple, 9 home runs, and 48 RBIs so far this season. Kazuma Okamoto leads Toronto with a team-high 33 home runs and 89 RBIs alongside 130 hits and 24 doubles on the year. Vladimir Guerrero Jr. has contributed 140 hits with 25 doubles, 9 home runs, and 56 RBIs, while Andres Gimenez has logged 113 hits with 25 doubles, a triple, 9 home runs, and 58 RBIs. George Springer has added 114 hits with 22 doubles, 2 triples, 15 home runs, and 54 RBIs for Toronto up to this point in the season.

Cincinnati Reds @ Toronto Blue Jays Betting Trends: September 25, 2026

 

Why the Toronto Blue Jays will win

 

Why the Cincinnati Reds will win

Total Runs Facts

Toronto Blue Jays Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Cincinnati Reds vs. Toronto Blue Jays Prediction

I’m on the Reds in this one. Nick Lodolo’s had his ups and downs this season but I trust his game more away from hitter friendly Great American, and the Jays are not only struggling right now but have struggled more against lefties this season. I think the Reds take care of business in this one so give me Cincinnati to draw first blood here.

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