Twins vs Orioles Prediction 5/6/25 MLB Picks Today

In this article, we will formulate a Twins vs Orioles Prediction for this MLB game on Tuesday, May 6th, at Target Field. Let’s take a look at a Minnesota Twins vs Baltimore Orioles pick. 

Twins Win A Series

It has been quite the trying season, but they are coming off a series win against the Boston Red Sox over the weekend. On Sunday, the Twins almost blew it again, but they still ended up coming away with the 5-4 victory. Byron Buxton had a strong game, hitting a home run, and he has been one of the bright spots for the team this year. 


The Twins are averaging 3.8 runs while their pitching is giving up 3.71 runs per game. The offense is ranked 23rd while the pitching is ranked 9th. As a team, they are batting only .236, which is 22nd. Getting the start for the Twins will be Pablo Lopez who sits with a 2-2 record and an ERA of 2.45. Against the Cleveland Guardians, he went 6.1 innings giving up four hits and two runs. Royce Lewis has been activated from the injured list, and getting him back is a big boost. 

Why the Twins Will Beat the Orioles

Orioles are Struggling

The Orioles are struggling heading into this game and they have lost two games in a row. On Saturday they lost 4-0 and in the last game they on Sunday they lost 11-6 at the hands of the Kansas City Royals. Even though they lost Jackson Holliday did have a strong game hitting two home runs. The offense wasn’t the problem it was the pitching that didn’t give them any shot to come away with a win. 

The Orioles are averaging 3.91 runs while their pitching is giving up 5.58 runs per game. The offense is ranked 20th while the pitching is ranked 28th. They have a negative run differential of -1.667 which is 28th. Getting the start for the Orioles will be Cade Povich who sits with a 1-2 record and an ERA of 5.16. Against the New York Yankees in his last start, he went 4.2 innings, giving up three hits and three runs. 

Total Runs Facts

Twins vs Orioles Prediction

The Twins finally have some confidence after what they did against the Boston Red Sox and they’re going to continue that success here. Povich hasn’t been the pitcher he was last season and he’s not going to be very good here. The Twins offense hasn’t been elite this season, but they are going to find success here. Pablo Lopez has been strong this season ,and he currently sits with an ERA of 2.45. The Orioles offense won’t be keeping up. Back the Twins on the money line to cash.

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