White Sox vs Cubs Prediction 7-26-25 MLB Picks

The Chicago Cubs and Chicago White Sox meet Saturday in MLB action at Sutter Health Park. Here’s a White Sox vs Cubs Prediction. This article will include a White Sox vs Cubs Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 60-43 on the year and play the Brewers, Orioles, and Reds next. The Chicago Cubs are batting .256 on the season, have a .324 OBP, and a .445 slugging percentage. The Chicago Cubs pitching staff has a 3.93 ERA and a 1.23 WHIP. Nico Hoerner leads the Chicago Cubs with 108 hits and 41 RBI, while Pete Crow-Armstrong and Kyle Tucker have combined for 209 hits and 132 RBI.

Cade Horton gets the ball for the Chicago Cubs, and he is 3-3 with a 4.04 ERA and 47 strikeouts this season. This will be Horton’s second career game against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 38-66 on the year and play the Phillies, Angels, and Mariners next. The Chicago White Sox are batting .227 on the season, have a .300 OBP, and a .360 slugging percentage. The Chicago White Sox pitching staff has a 4.08 ERA and a 1.38 WHIP. Miguel Vargas leads the Chicago White Sox with 84 hits and 41 RBI while Lenyn Sosa and Chase Meidroth have combined for 158 hits and 52 RBI.

Aaron Civale gets the ball for the Chicago White Sox, and he is 2-6 with a 4.76 ERA and 42 strikeouts this season. Civale is 0-0 with a 1.61 ERA and 16 strikeouts in his career against the Chicago Cubs.

Why the Chicago White Sox will win

Why the Chicago Cubs will win

Chicago White Sox Player Prop Facts

Chicago Cubs Player Prop Facts

White Sox vs Cubs Prediction

We’ve made a killing blindly fading the White Sox over the years, but six wins in their last seven games is worth looking at. Horton has been hittable this season, especially on the road, where he has a 6.35 ERA and .313 allowed batting average in 28.1 innings. This winning stretch is unlikely going to continue for much longer, but the White Sox have made money hand over fist in the second half. I’ll take the White Sox on Saturday.

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