White Sox vs Red Sox Prediction 4/11/25 MLB Picks Today

In this article, we will formulate a White Sox vs Red Sox prediction for this MLB game on Friday, April 11th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 2-10 this year after they were swept by the Guardians in their last series by scores of 0-1, 2-3, and 1-6. In that game three loss, the White Sox took a 1-0 lead in the top of the first inning, but they allowed two in the bottom of the first and never got anything else going in the loss. The White Sox recorded five hits and committed two errors, while they were led by Sosa, who recorded two hits in the loss. Chicago started Cannon, who allowed seven hits and six earned runs for the loss, while Wilson and Clevinger combined for 2.2 scoreless innings out of the bullpen. 

Prior to that series, the White Sox were swept by the Tigers in three games and lost two out of three against the Twins. The Chicago pitching staff has a 3.96 ERA with a 1.29 WHIP and a .217 opponent batting average, while the offense has scored 35 runs with a .199 batting average and a .273 on-base percentage this season. Nick Maton has led Chicago with two home runs and two RBIs, while Brooks Baldwin has added one home run and five RBIs this year. The projected starting pitcher for Chicago is Davis Martin, who is 0-1 with a 5.73 ERA and a 1.55 WHIP over 11.0 innings pitched this season. 

Boston Red Sox Betting Preview

The Boston Red Sox are 7-7 this season after they lost three out of four games against Toronto by scores of 2-6, 1-6, 1-2, and 4-3. In that game four win, the Red Sox trailed 2-1 in the seventh, but they were able to manufacture a run in the eighth and picked up the win in extra innings. Boston recorded eight hits, and they committed two errors in the game, while they were led by Duran, Bregman, and Story, who all had one RBI in the win. The Red Sox started Buehler, who allowed four hits and one earned run over 6.1 innings, while Bernardino ended up getting the win in the 10th. 

Prior to that series, the Red Sox swept the Cardinals in three games and won two out of three against the Orioles. The Boston pitching staff has a 3.86 ERA with a 1.34 WHIP and a .269 opponent batting average, while their offense has scored 71 runs with a .255 batting average and a .331 on-base percentage this season. Wilyer Abreu has led Boston with three home runs and 12 RBIs, while Alex Bregman has added two home runs and 12 RBIs this year. The projected starting pitcher for Boston is Sean Newcomb, who is 0-1 with a 5.19 ERA and a 2.19 WHIP over 8.2 innings pitched this season. 

Why the White Sox will beat the Red Sox

• The home team has won each of the White Sox’s last six games.
• The Red Sox have lost each of their last six night games after playing the previous day.
• The Red Sox have failed to cover the run line in each of their last four games.
• The underdogs have covered the run line in five of the Red Sox’s last six games.
• The White Sox have led after 3 innings in three of their last four home night games.
• The Red Sox have trailed after 5 innings in six of their last seven road games against American League opponents that held a losing record.

Why the Red Sox will beat the White Sox

• The White Sox have lost each of their last eight games.
• The Red Sox have won each of their last 11 games as road favorites following a home win.
• The Red Sox have covered the run line in each of their last six road games against American League opponents following a home win.
• The White Sox have failed to cover the run line in nine of their last 10 games as home underdogs against AL East opponents following a loss.
• The Red Sox have led after 3 innings in six of their last seven night games against the White Sox at Rate Field.
• The Red Sox have led after 5 innings in each of their last five games against AL Central opponents.

Total Runs Facts

• Each of the Red Sox’s last eight games as favorites against American League opponents have gone UNDER the total runs line.
• Five of the White Sox’s last six night games against American League opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the White Sox’s last six night games at Rate Field.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 14 of the Red Sox’s last 16 night games against American League opponents.

Chicago White Sox Player Prop Facts

• Andrew Vaughn has scored at least one run in each of the White Sox’s last four home games against the Red Sox.
• Andrew Benintendi has recorded at least one hit in each of his last seven appearances against former teams.
• Omar Narvaez has recorded at least one Single in six of his last seven appearances with his team as an underdog against AL East opponents.
• Omar Narvaez has recorded at least one RBI in four of his last five appearances with his team as an underdog against the Red Sox.
• Omar Narvaez has recorded a Double in four of his last five home appearances against AL East opponents.
• Omar Narvaez has hit a home run in four of his last five appearances with his team as an underdog against the Red Sox.

Boston Red Sox Player Prop Facts

• Trevor Story has hit a home run in two of his three previous road appearances against the White Sox.
• Trevor Story has scored a run in each of the Red Sox’s last three games as road favorites.
• Alex Bregman has recorded at least one Single in 11 of his last 12 appearances at Rate Field against opponents that held a losing record.
• Alex Bregman has recorded at least one hit in each of his last 13 road appearances against AL Central opponents.
• Connor Wong has recorded an RBI in each of his last four appearances against AL Central opponents.
• Connor Wong has recorded a Double in three of the Red Sox’s last four games as favorites against AL Central opponents.

White Sox vs Red Sox Prediction 

Chicago comes into this matchup looking to snap a losing streak, but they need to find more offense, as they have scored two runs or fewer in four of their last five games. Boston was able to avoid the four-game sweep on Thursday afternoon, but their offense is also struggling right now. Both of these pitchers have had plenty of issues early in this season, and I think this is exactly what both lineups need. I expect both teams to have a big day at the plate, and I like the over here.