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White Sox vs Red Sox Prediction 4/13/25 MLB Picks Today

Boston Red Sox (7-9) vs. Chicago White Sox (4-10)
April 13, 2025 2:10 pm EDT
The Line: Chicago White Sox 195 / Boston Red Sox -238; Over/Under: 6.5
(Get latest betting odds)

In this article we will formulate a White Sox vs Red Sox prediction for this MLB game on Sunday, April 13th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 4-10 this season after they won the first two games in this series by scores of 11-1 and 3-2. In that game two win, the White Sox trailed 2-0 in the fifth inning, but they tied the game in the sixth and won it in the ninth. Chicago recorded just four hits in the game and they were led by Robert Jr., who went 1-3 with one home run, two RBIs, and one walk in the win. Chicago started Perez, who allowed five hits and two earned runs over 4.2 innings, while Gilbert pitched the final out of the ninth and was credited with the win. 

Prior to this series, the White Sox were swept by the Guardians in three games and by the Tigers in three games. The Chicago pitching staff has a 3.59 ERA with a 1.28 WHIP and a .217 opponent batting average, while the offense has scored 49 runs with a .206 batting average and a .279 on base percentage this season. Nick Maton has led Chicago with two home runs and two RBIs, while Brooks Baldwin has added one home run and seven RBIs this year. The projected starting pitcher for Chicago is Shane Smith, who is 0-0 with a 1.54 ERA and a 0.77 WHIP over 11.2 innings pitched this season. 

Boston Red Sox Betting Preview

The Boston Red Sox are 7-9 this year after they dropped game two in this series by a score of 3-2 on Saturday. Boston got two runs in the fifth inning, but they couldn’t find anymore scoring in the game for the loss. The Red Sox recorded seven hits in the game and they were led by Gonzalez and Rafaela, who both had one RBI in the loss. Boston started Fitts, who allowed just two hits over 5.0 innings of work, while Kelly allowed two earned runs in 1.2 innings and Chapman allowed one earned run in the bottom of the ninth for the loss. 

Prior to this series, the Red Sox lost three out of four against the Blue Jays and swept the Cardinals in three games. The Boston pitching staff has a 3.92 ERA with a 1.35 WHIP and a .267 opponent batting average, while their offense has scored 74 runs with a .250 batting average and a .330 on base percentage this season. Wilyer Abreu has led Boston with three home runs and 12 RBIs, while Alex Bregman has added two home runs and 12 RBIs this year. The projected starting pitcher for Boston is Garrett Crochet, who is 1-1 with a 1.45 ERA and a 1.13 WHIP over 18.2 innings pitched this season. 

Why the Red Sox will beat the White Sox

  • The White Sox have lost seven of their last eight games against teams that held a losing record.
  • The Red Sox have won 13 of their last 16 games against the White Sox following a road loss.
  • The White Sox have failed to cover the run line in five of their last six games against AL East opponents that held a losing record.
  • The Red Sox have covered the run line in four of their last five games as favorites against AL Central opponents following a loss.
  • The Red Sox have led after 5 innings in each of their last seven Sunday games as favorites.

Total Runs Facts

  • Nine of the Red Sox’s last 10 games as favorites against American League opponents have gone UNDER the total runs line.
  • Three of the White Sox’s last four day games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last 11 day games between the Red Sox and White Sox.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Red Sox’s last seven day games at Rate Field.

Chicago White Sox Player Prop Facts

  • Luis Robert has hit at least one home run in four of his last five home appearances against the Red Sox after playing the previous day.
  • Luis Robert has recorded at least one RBI in seven of his eight previous home appearances against the Red Sox after playing the previous day.
  • Andrew Benintendi has recorded a Double in three of his last four home appearances against former teams.
  • Josh Rojas has scored at least one run in five of his last six appearances at Rate Field.
  • Omar Narvaez has recorded a Single in 10 of his last 11 home appearances against AL East opponents that held a losing record.
  • Andrew Benintendi has recorded at least one hit in each of his last 11 home appearances against opponents that held a losing record.

Boston Red Sox Player Prop Facts

  • Rafael Devers has hit a home run in five of his last six Sunday day appearances with the Red Sox as favorites.
  • Trevor Story has recorded at least one Single in each of his last six appearances against AL Central opponents.
  • Jarren Duran has scored at least one run in nine of his last 10 appearances in day games against teams that held a losing record.
  • Alex Bregman has recorded at least one hit in 14 of his last 15 road appearances against AL Central opponents.
  • Connor Wong has recorded an RBI in each of his last four appearances against AL Central opponents.
  • Connor Wong has recorded a Double in each of his last three appearances in day games against teams that held a losing record.

White Sox vs Red Sox Prediction 

Boston comes into this matchup looking to avoid being swept, but they have lost five of their last six games and they have scored two runs or fewer in all five of those losses. Chicago has half of their wins so far this season in this series and they will look for a very rare sweep here. The White Sox have had a decent start with their pitching staff this year and they are going with Smith, who has allowed two earned runs over 11.2 innings pitched. Boston is starting Crochet, who has allowed three earned runs over 18.2 innings this season. I think Crochet is the better pitcher in this matchup and I like Boston to cover the run line here. 

David Racey's Free Pick: Red Sox -1.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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