Yankees vs Cardinals Prediction 8/17/25 MLB Picks Today

In this article, we will formulate a Yankees vs Cardinals Prediction for this MLB game on Sunday, August 17th at the Busch Stadium in the third game of this series, with the Yankees having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 61-63 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 35-29 home record and are 61-57 in over/under They are coming off an 8-12 home defeat by the Yankees, and have four consecutive losses. Under is 6-3 in their last 9 games and are playing the Marlins and the Rays next.

The Cardinals have a .250 batting average this season, .318 OBP and .388 Slugging percentage. Saint Louis’ pitching staff has a 4.25 ERA and 1.29 WHIP. Brendan Donovan leads the Cardinals with 118 hits, while Alec Burleson is the team’s best hitter with a .284 batting average. Wilson Contreras leads the team in RBI, with 65, adding a team-high 16 home runs.

Miles Mikolas (R) is the projected starting pitcher for the Cardinals, and he has a 6-9 record, 4.97 ERA and 1.28 WHIP.

New York Yankees Preview

The New York Yankees have a 66-57 record this season and are sitting on the third place of the AL East. The Yankees have a 29-32 road record and are 55-63 in over/under. They are coming off a 12-8 road victory over the Cardinals, and are 4-1 in their last 5 games. Under is 4-2 in their last 6 games and are playing the Rays and the Red Sox next.

The Yankees have a .250 batting average this season, .330 OBP and .447 Slugging percentage. New York’s pitching staff has a 4.04 ERA and 1.25 WHIP. Aaron Judge leads the Yankees with 136 hits, adding team-highs both in RBI, with 91 and in home runs, with 39. He is also the team’s best hitter, with a .333 batting average.

Will Warren (R) is the projected starting pitcher for the Yankees, and he has a 7-5 record, 4.34 ERA and 1.27 WHIP.

Why the St. Louis Cardinals will win

Why the New York Yankees will win

Total Runs Facts

Matchup/League Facts

Yankees vs Cardinals Prediction

The Cardinals are 7-4 in their last 11 meetings against the Yankees, and are 5-3 in their last 8 meetings in Saint Louis. Over is 4-1 in their last 5 meetings.

In this Yankees vs Cardinals Prediction, the Yankees are coming as -150 road favorites. I don’t trust either pitcher in this matchup, as they both have a combined 9.31 ERA, and Warren has been terrible on the road for the Yankees, with a 6.48 road ERA, and Mikolas has been in mediocre form for the Cardinals, with a 5.11 ERA across his last 5 starts. The Yankees have the third-best offense in the league with 5.1 runs per game, and with yesterday’s game going way over the total with 20 total runs, I like another high-scoring affair today. Take the over 9 runs in this one.

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