NFL Picks

Seattle Seahawks vs San Francisco 49ers 12/5/21 NFL Picks, Predictions, Odds

San Francisco 49ers (6-5) vs. Seattle Seahawks (3-8)
December 5, 2021 4:25 pm EDT
The Line: Seattle Seahawks +3.5 / San Francisco 49ers -3.5; Over/Under: +46
(Get latest betting odds)

The Seattle Seahawks and San Francisco 49ers square off in week 13 NFL action from Lumen Field in Seattle on Sunday afternoon.

The San Francisco 49ers will try to build on a 3rd straight win after a 34-26 win over Minnesota last time out. Jimmy Garoppolo has thrown for 2,342 yards, 13 touchdowns and 8 picks on 66.8% passing while Elijah Mitchell leads San Fran’s ground attack with 693 rushing yards and 4 scores. Deebo Samuel leads the Niners in receiving with 56 grabs for 1006 yards and 5 TDs while Brandon Aiyuk and George Kittle each have 400+ receiving yards as well this season. On defense, Fred Warner leads the Niners with 92 total tackles while Nick Bosa has a team-high 11 sacks on the year.

The Seattle Seahawks will look to rebound from a 17-15 loss at the hands of the Washington Football team last time out. Russell Wilson’s thrown for 1,811 yards, 12 touchdowns and 3 interceptions on 64.9% passing while Alex Collins has 395 rushing yards and Tyler Lockett has a team-high 50 catches for 813 receiving yards and 3 scores this season. D.K. Metcalf also leads Seattle’s receiving group with 8 touchdowns, logging 47 catches for 650 yards this season. On defense, Bobby Wagner leads the Seahawks with 128 total tackles while Jordyn Brooks has 113 total tackles and Darrell Taylor has 5 sacks. Quandre Diggs also has a team-high three interceptions for the Seattle secondary this season.

San Francisco is 4-1 ATS in their last 5 games overall and 4-10 ATS in their last 14 games as a favorite while the over is 7-1 in their last 8 games following an ATS win. Seattle is 14-6 ATS in their last 20 games as an underdog and 2-5-1 ATS in their last 8 games in December while the under is 6-0 in their last 6 games as an underdog.

I get the allure of Seattle catching points at home with the 12th man, but the bottom line here is that the Seahawks are a disaster right now and a matchup with a San Fran team that’s on the hunt isn’t going to help matters. The Niners don’t have a ton going their way right now, but the Seahawks are in panic mode and I don’t like backing teams in panic mode. Give me San Fran here.


Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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