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San Francisco 49ers at Seattle Seahawks - 9/17/17 NFL Pick, Odds, and Prediction

San Francisco 49ers (0-1) at Seattle Seahawks (0-1)

NFL Football: Sunday, September 17, 2017 at 4:25 pm (CenturyLink Field)

The Line: Seattle Seahawks -14 -- Over/Under: 42 See the Latest Odds

TV: FOX

The San Francisco 49ers and Seattle Seahawks meet Sunday in NFL action at CenturyLink Field.

The San Francisco 49ers would love a bounce back performance after getting beat up by the Carolina Panthers, 23-3. The San Francisco 49ers have lost 14 of their last 16 road games. Brian Hoyer is completing 68.6 percent of his passes for 193 yards, zero touchdowns and one interception. Hoyer has zero touchdown passes in four of his last seven games. Pierre Garcon and Carlos Hyde have combined for 113 receiving yards on 12 catches while George Kittle has five receptions. The San Francisco 49ers ground game is averaging 51 yards per contest, and Hyde leads the way with 45 yards on nine carries. Defensively, San Francisco is allowing 23 points and 287 yards per game. Jaquiski Tartt leads the San Francisco 49ers with seven tackles, Rashard Robinson has one tackle for loss and Reuben Foster has one pass deflection. 

San Francisco 49ers at Seattle Seahawks - 9/17/17 NFL Pick, Odds, and Prediction

USA TODAY Sports

The Seattle Seahawks also are looking for their first victory after losing to the Green Bay Packers, 17-9. The Seattle Seahawks have won 10 of their last 12 home games. Russell Wilson is completing 51.9 percent of his passes for 158 yards, zero touchdowns and zero interceptions. Wilson has one or less touchdown passes in seven of his last eight games. Doug Baldwin and Paul Richardson have combined for 122 receiving yards on eight catches while Chris Carson has one reception. The Seattle Seahawks ground game is averaging 90 yards per contest, and Wilson leads the way with 40 yards on two carries. Defensively, Seattle is allowing 17 points and 370 yards per game. Earl Thomas leads the Seattle Seahawks with 11 tackles, Michael Bennett has 1.5 sacks and Nazair Jones has one interception.

The 49ers are 5-12-1 ATS in their last 18 road games, 1-5 ATS in their last 6 games in September and 4-12 ATS in their last 16 games overall. The Seahawks are 5-1 ATS in their last 6 home games, 2-5 ATS in their last 7 games in September and 1-4 ATS in their last 5 games overall. The 49ers are 0-5-1 ATS in their last 6 meetings in Seattle, 1-9-1 ATS in their last 11 meetings and the favorite is 3-1-1 ATS in their last 5 meetings.

These two teams have a history of playing tight, physical games and the last meeting was decided by just two points. So, instead of playing with massive chalk, I'm going to side with the over on the total. This feels like one of those games where the 49ers struggle to move the ball and the defense caves due to being on the field so long. Wilson is likely going to have his breakout offensive game after being in a slump dating back to last year, and the Seahawks come close to this total by themselves. A score of 35-14 is reasonable, putting us over the number and avoiding any chance of getting screwed on a backdoor cover. 

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