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Dallas Cowboys at San Francisco 49ers - 10/22/17 NFL Pick, Odds, and Prediction

Dallas Cowboys (2-3) at San Francisco 49ers (0-6)

NFL Football: Sunday, October 22, 2017 at 4:05 pm (Levi's Stadium)

The Line: San Francisco 49ers +4 -- Over/Under: 47 See the Latest Odds

TV: FOX

Down at Levi’s Stadium in Santa Clara on Sunday, the Dallas Cowboys and the San Francisco 49ers will be meeting up in NFL activity. 

The Cowboys enter this game with a 2-3 record, beating the Giants and Cardinals while falling to Denver, the Rams and Green Bay. In that Packers game, Cowboys QB Dak Prescott went 25-of-36 for 251 yards, three TDs and a score while Ezekiel Elliott managed 29 carries for 116 yards. 

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Dallas Cowboys at San Francisco 49ers - 10/22/17 NFL Pick, Odds, and Prediction

USA TODAY Sports

On the year so far, Prescott has 1192 yards, 11 touchdowns and four picks; Elliott leads the Cowboys with 393 yards, 105 attempts and two TDs. Dez Bryant is the lead Dallas receiver with 264 yards and three TDs on 21 catches. 

The Niners skid into this one with a 0-6 record on the season, losing to the Panthers, Seahawks, Rams, Cardinals, Colts and Redskins. In that Redskins game, 49ers QB CJ Beathard posted 245 yards, one TD and one pick, and Carlos Hyde led an anemic rush on 13 carries, 28 yards and two TDs. 

On the season, Hyde leads San Francisco with 86 carries, 360 yards and four touchdowns, and Pierre Garcon is the top receiver with 434 yards and 33 receptions on 56 targets. 

The Cowboys are 4-1 ATS in their last five games in Week 7 and 4-1 ATS versus a team with a losing record. Dallas is also 2-5 ATS in their last seven games following an ATS loss and 3-8 ATS in their last 11 versus the NFC. 

Meanwhile, the 49ers are 4-0 ATS in the last four versus the NFC and 5-1 ATS in their last six games following a straight-up loss. San Francisco is also 4-1 ATS in the last five games overall and 2-6 ATS in their last eight games in October. 

The Cowboys have been putting up points over their last two losses, but the defense hasn’t been helping out. Between the Rams and Packers, Dallas gave up 70 points and scored 61 overall. As for San Fran, they look pretty bad but haven’t been losing games by much. The Niners’ last five losses have come by three points or fewer. I’m going to go with the 49ers to hang around here and cover, but lose all the same.

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