Detroit Lions vs Buffalo Bills 11/24/22 NFL Picks, Predictions, Odds

Randy ChambersNovember 24, 2022
Detroit Lions vs Buffalo Bills 11/24/22 NFL Picks, Predictions, Odds player photo
Credit: USA Today Sports

The Detroit Lions and Buffalo Bills clash on Thanksgiving week 12 NFL action at Ford Field. The Buffalo Bills have won 5 of their last 7 games. The Detroit Lions look to build on their 3-game winning streak.

The Buffalo Bills have won 3 of their last 5 road games. Josh Allen is completing 64.7 percent of his passes for 2,930 yards, 21 touchdowns and 10 interceptions. Stefon Diggs and Gabe Davis have combined for 1,645 receiving yards and 13 touchdowns, while Dawson Knox has 31 receptions. The Buffalo Bills ground game is averaging 134 yards per contest, and Allen leads the way with 483 yards and 4 touchdowns. Defensively, Buffalo is allowing 17.4 points and 327.4 yards per game. Tremaine Edmunds leads the Buffalo Bills with 65 tackles, Von Miller has 8 sacks and Jordan Poyer has 4 interceptions.

The Detroit Lions have lost 3 of their last 5 home games. Jared Goff is completing 63.9 percent of his passes for 2,442 yards, 15 touchdowns and 7 interceptions. Amon-Ra St. Brown and Josh Reynolds have combined for 951 receiving yards and 5 touchdowns, while Kalif Raymond has 26 receptions. The Detroit Lions ground game is averaging 132.8 yards per contest, and Jamaal Williams leads the way with 668 yards and 12 touchdowns. Defensively, Detroit is allowing 28.2 points and 415.9 yards per game. Alex Anzalone leads the Detroit Lions with 77 tackles, Aidan Hutchinson has 5.5 sacks and Kerby Joseph has 3 interceptions.

The Bills are 12-5-1 ATS in their last 18 games in November and 6-1-1 ATS vs. a team with a losing record. The Lions are 7-2 ATS in their last 9 home games and 13-6 ATS in their last 19 games overall. The under is 6-2 in Bills last 8 games overall. The over is 9-3 in Lions last 12 games overall. The underdog is 4-1 ATS in their last 5 meetings.

The Buffalo Bills are going to be clear favorites because they're the better team, and they were just at Ford Field last week, so they know the field and have fans who already traveled. However, the Detroit Lions have quietly won 3 straight games and while the defense has issues, they're still a top-10 offense that can make things hairy for opponents. The Lions play hard and are a lot more competitive than their record would suggest. This is a lot of points for a quick turnaround, and you're giving a quality offense more than a touchdown. I'll take a shot with the Lions and the points.

Randy Chambers's Free Pick:Detroit Lions +9.5
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Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA and is more than familiar with what it takes to navigate a 150 game college basketball Saturday and a 162 game MLB schedule. Randy has done it all. Follow Randy Chambers on Twitter or catch him on the PickDawgz YouTube channel.