Bills vs Chiefs Prediction 11/2/25 NFL Picks Today

The Kansas City Chiefs and Buffalo Bills meet Sunday in NFL action at Highmark Stadium. Here’s a Bills vs Chiefs Prediction. This article will include a Bills vs Chiefs Pick.

Kansas City Chiefs Betting Preview

The Kansas City Chiefs beat the Raiders and Commanders, and they play the Broncos next. The Kansas City Chiefs have won 3 straight games. Patrick Mahomes is completing 67 percent of his passes for 2,009 yards, 17 touchdowns, and 4 interceptions. Hollywood Brown and Travis Kelce have combined for 790 receiving yards and 7 touchdowns, while Tyquan Thornton has 14 receptions.

The Kansas City Chiefs ground game is averaging 126.5 yards per contest, and Isiah Pacheco leads the way with 329 yards and 1 touchdown. Defensively, Kansas City is allowing 16.4 points and 277.8 yards per game. Chamarri Conner leads the Kansas City Chiefs with 63 tackles, George Karlaftis has 4.5 sacks and Chris Roland-Wallace has 1 interception.

Buffalo Bills Betting Preview

The Buffalo Bills lost to the Falcons, beat the Panthers, and they play the Dolphins next. The Bills have won 5 of their last 7 games. Josh Allen is completing 68 percent of his passes for 1,560 yards, 12 touchdowns, and 4 interceptions. Khalil Shakir and Dalton Kincaid have combined for 666 receiving yards and 6 touchdowns, while Keon Coleman has 27 receptions.

The Buffalo Bills ground game is averaging 164.4 yards per contest, and James Cook leads the way with 753 yards and 7 touchdowns. Defensively, Buffalo is allowing 20.9 points and 312.1 yards per game. Cole Bishop leads the Buffalo Bills with 34 tackles, Ed Oliver has 3 sacks and AJ Epenesa has 1 interception.

Why the Buffalo Bills will win

Why the Kansas City Chiefs will win

Total Points Facts

Buffalo Bills Player Prop Facts

Kansas City Chiefs Player Prop Facts

Matchup/League Facts

Bills vs Chiefs Prediction

The Chiefs should be favored, as they look like a team that’s getting its act together and becoming the Chiefs we all know and love. The Bills have also had issues getting over the hump when playing the Chiefs. However, the Bills have the offense to go toe-to-toe with the Chiefs, and this will be just the fourth time since 2021 where they’re a home underdog. The Bills have outright won their last 4 home games as an underdog. The Chiefs have failed to cover 5 of their last 8 road games as a favorite. Four of the last five meetings between the Bills and Chiefs have been decided by 4 or fewer points. The value is with the Bills and the points. I’ll take them.

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