Bears vs Cowboys Prediction 9/21/25 NFL Picks Today

The Dallas Cowboys and the Chicago Bears meet Sunday in NFL action from Soldier Field. Here’s a Bears vs Cowboys prediction. We will look at this from a betting perspective and determine the best Bears vs Cowboys pick.

Dallas Cowboys Betting Preview

This year the Cowboys’ opener pitted them against their rival (and Super Bowl champion) Philadelphia Eagles. Dallas kept pace for the first half but couldn’t score after the break in a tough road loss 24-20. Quarterback Dak Prescott went 21-of-34 for 188 yards in the defeat, and Javonte Williams led the rush on 15 carries for 54 yards and two scores. CeeDee Lamb was the top receiver with seven catches for 110 yards.

In another divisional rivalry matchup with the New York Giants on Sunday, the Cowboys played a wild game. Dallas went into the break with a 13-10 deficit, then after a 21-20 fourth quarter we had overtime. The Cowboys would end up kicking the game-winning field goal for a hard-fought 40-37 victory. Prescott was 38-of-52 for 361 yards, two scores and an interception. Williams again led the rush, this time on 18 carries for 97 yards and a score. Lamb was again on top of the receivers with his nine grabs for 112 yards. Jake Ferguson also had nine catches, totaling 78 yards in the tight victory.

Chicago Bears Betting Preview

Over on the Bears’ side, they played their division-mate Minnesota Vikings in the opener this year. Chicago was up 17-6 going into the fourth quarter, then got outscored 21-7 the rest of the way for a rough loss 27-24. Caleb Williams managed a 21-of-35 line for 210 yards and a touchdown while also leading the rush with six totes for 58 yards and another score. DJ Moore was the leading team receiver in the loss, totaling 68 yards on three grabs.

Matched up against the Detroit Lions in game two, the Bears were in for a long day. Chicago coughed up double-digit points in each of the four quarters (including 28 in the first half) on the way to a rough loss 52-21. Williams was 19-of-30 for 207 yards, two touchdowns and an interception this time, and D’Andre Swift carried 12 times for 63 yards and a score. Rome Odunze had a nice day though, catching seven balls for 128 yards and two touchdowns. Moore would add five catches for 46 yards as well.

Dallas Cowboys @ Chicago Bears Betting Trends: Week 3

 

Why the Chicago Bears will win

Why the Dallas Cowboys will win

Total Points Facts

Chicago Bears Player Prop Facts

Dallas Cowboys Player Prop Facts

Matchup/League Facts

Bears vs Cowboys Prediction

I’ll take a stab on the Bears in this one, but I’ll likely stay away in reality. You could probably call this game either way. With one coming off a blowout loss to a good team, and the other coming off an overtime win versus a bad team, it’s anyone’s guess how this one will go. In any case, Chicago’s defense got demolished by the Lions to the tune of 511 yards (334 passing), 8.8 yards per play and 25 first downs. The Bears coughed up a couple of turnovers themselves and had eight penalties along the way. Through two games so far, Chicago hasn’t scored terribly—21 or more in both games and a combined 45 together. On defense the Bears have given up 79 combined across that same pair, however. Dallas might be able to put up a sizable total here.

Speaking of the Cowboys, they committed 12 penalties in a sloppy overall game (26 total flags) versus the Giants, and also gave up a whopping 506 yards (422 passing) on defense. All things considered the third-down stands (6-of-14) weren’t too bad though, and Dallas did get an interception. Offensively the Cowboys posted 478 yards (343 passing), 5.8 yards per play and 32 first downs. This should be another good opportunity to flex their muscles on offense, but the Bears should be able to put up a few points themselves.

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