Chiefs vs Colts Prediction 11/23/25 NFL Picks Today

The Indianapolis Colts and Kansas City Chiefs meet Sunday in NFL action at GEHA Field. Here’s a Chiefs vs Colts Prediction. This article will include a Chiefs vs Colts Pick.

Indianapolis Colts Betting Preview

The Indianapolis Colts lost to the Steelers, beat the Falcons, and they play the Texans next. The Indianapolis Colts have won 5 of their last 6 games. Daniel Jones is completing 69.9 percent of his passes for 2,659 yards, 15 touchdowns, and 7 interceptions. Tyler Warren and Alex Pierce have combined for 1,202 receiving yards and 4 touchdowns, while Micheal Pittman Jr. has 54 receptions.

The Indianapolis Colts ground game is averaging 145.3 yards per contest, and Jonathan Taylor leads the way with 1,139 yards and 15 touchdowns. Defensively, Indianapolis is allowing 20.6 points and 327.6 yards per game. Nick Cross leads the Indianapolis Colts with 69 tackles, Laiatu Latu has 5 sacks and Mekhi Blackmon has 2 interceptions.

Kansas City Chiefs Betting Preview

The Kansas City Chiefs lost to the Bills and Broncos, and they play the Cowboys next. The Kansas City Chiefs have split their last 10 games. Patrick Mahomes is completing 64.5 percent of his passes for 2,625 yards, 18 touchdowns, and 6 interceptions. Hollywood Brown and Travis Kelce have combined for 1,060 receiving yards and 8 touchdowns, while Tyquan Thornton has 15 receptions.

The Kansas City Chiefs ground game is averaging 115.3 yards per contest, and Kareem Hunt leads the way with 353 yards and 6 touchdowns. Defensively, Kansas City is allowing 18.1 points and 296.8 yards per game. Nick Bolton leads the Kansas City Chiefs with 81 tackles, George Karlaftis has 5 sacks and Chris Roland-Wallace has 1 interception.

Why the Kansas City Chiefs will win

Why the Indianapolis Colts will win

Total Points Facts

Kansas City Chiefs Player Prop Facts

Indianapolis Colts Player Prop Facts

Matchup/League Facts

Chiefs vs Colts Prediction

A lot of people are going to be on the Colts and the points, as they’ve been a solid team all year and have had an extra week to prepare. The Chiefs are also experiencing a down year by their standards and are coming off two shaky losses. I get it, and I usually love my dogs that have the rest advantage. However, we’re getting the Chiefs at home as a reasonable favorite. You don’t get these chances often.

The Chiefs have won and covered four straight home games when favorites of 4 or fewer points. They’ve won those games by an average of 7.75 points. The Chiefs have covered 9 of their 14 home games when favorites of 4 or fewer points. I’ll side with the Chiefs and the reasonable number.

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