Jaguars vs Texans Prediction 9/21/25 NFL Picks Today

In this article we will formulate a Jaguars vs Texans prediction for this NFL game on Sunday, September 21st at EverBank Stadium in Jacksonville, Florida. Let’s take a look at the prediction for this week 3 matchup.

Jacksonville Jaguars Betting Preview

The Jacksonville Jaguars are 1-1 this year after they lost to Cincinnati by a score of 31-27 in their last game. Jacksonville was tied at seven after the first quarter and they led 17-10 at the half, but a back and forth second half ended with the Bengals scoring with 18 seconds left in the game. The Jaguars out gained Cincinnati by a total of 400-350, went 6-13 on third downs, and won the turnover battle by a margin of 3-2. Trevor Lawrence went 24-42 for 271 yards, three touchdowns, and two interceptions, while Travis Etienne Jr rushed 14 times for 71 yards. Parker Washington was the leading receiver for Jacksonville with five catches for 76 yards in the game. The Jacksonville defense recorded three sacks and six tackles for loss in the defeat. 


Jacksonville opened the season with a 26-10 win over Carolina at home in week one. The Jaguars are averaging 26.5 points per game with 219.5 passing yards and 169.5 rushing yards per game, while they are allowing 20.5 points against per game this season. Trevor Lawrence has completed 58.9% of his passes for 449 yards, four touchdowns, and three interceptions, while Dyami Brown has caught eight passes for 109 yards and one score. Travis Etienne Jr is the leading rusher with 30 carries for 214 yards so far this season. 

Houston Texans Betting Preview

The Houston Texans are 0-2 this season after they lost to Tampa Bay by a score of 20-19 last week. Houston led 10-7 after the first quarter, but they trailed 14-10 at the half. The Texans rallied to take a 19-14 lead late in the game, but allowed a touchdown to lose with six seconds left. Houston was out gained by a total of 360-266, went 2-9 on third downs, and tied the turnover battle at zero in the game. CJ Stroud went 13-24 for 207 yards and one touchdown, while Nick Chubb rushed 12 times for 43 yards and one score. Nico Collins was the leading receiver with three catches for 52 yards and one score in the loss. The Houston defense recorded four sacks and six tackles for loss in the defeat. 

Houston started the season with a 14-9 loss to the Rams on the road in week one. The Texans are averaging 14.0 points per game with 166.5 passing yards and 99.0 rushing yards per game, while they are allowing 17.0 points against per game this season. CJ Stroud has completed 62.7% of his passes for 395 yards, one touchdown, and one interception, while Nico Collins has caught six passes for 77 yards and one score. Nick Chubb has led the ground game with 25 carries for 103 yards and one touchdown this year. 

Why the Jaguars will beat the Texans

Total Points Facts

Jacksonville Jaguars Player Prop Facts

Houston Texans Player Prop Facts

Matchup/League Facts

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Jaguars vs Texans Prediction 

Both of these teams come into this matchup after picking up disappointing losses last weekend and will try to bounce back here. Houston has looked awful on offense and Stroud has not played well, but their defense has been strong. Jacksonville let Jake Browning beat them last week, so their defense is searching for answers. Both of these teams have some major flaws, but I refuse to back Houston until I see improvement from Stroud. Take the Jaguars here. 

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